10-(β-Hydroxypropyl)phenothiazine

Base Information

Chemical Name:10-(β-Hydroxypropyl)phenothiazine
CAS No.:32209-47-5
Molecular Formula:C₁₅H₁₅NOS
Molecular Weight:257.356
Hs Code.:
Mol file:32209-47-5.mol

Synonyms:10-(β-Hydroxypropyl)phenothiazine;α-Methyl-10H-phenothiazine-10-ethanol;α-Methyl-phenothiazine-10-ethanol

Suppliers and Price of 10-(β-Hydroxypropyl)phenothiazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
α-Methyl-phenothiazine-10-ethanol
500 mg
$ 675.00

Medical Isotopes, Inc.
α-Methyl-phenothiazine-10-ethanol
100 mg
$ 650.00

Total 3 raw suppliers

Chemical Property of 10-(β-Hydroxypropyl)phenothiazine

Chemical Property:

Melting Point:78 °C
Boiling Point:185-190 °C(Press: 0.3 Torr)
PKA:14.52±0.20(Predicted)
PSA：48.77000
Density:1.233±0.06 g/cm3(Predicted)
LogP:3.73510
Storage Temp.:-20°C Freezer
Solubility.:Chloroform (Slightly), Methanol (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

α-Methyl-phenothiazine-10-ethanol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 10-(β-Hydroxypropyl)phenothiazine

There total 2 articles about 10-(β-Hydroxypropyl)phenothiazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 92-84-2
10H-phenothiazine

: 75-56-9,16033-71-9
methyloxirane

: 32209-47-5
1-(10H-phenothiazin-10-yl)propan-2-ol

Guidance literature:: With methyllithium; 1.) ether, r.t., 30 min, 2.) r.t., 1 h;
DOI:10.1002/ardp.19813140812

Reference yield:

: 92-84-2
10H-phenothiazine

: 32209-47-5
1-(10H-phenothiazin-10-yl)propan-2-ol

Guidance literature:: With methyloxirane; In 5,5-dimethyl-1,3-cyclohexadiene; water;

Reference yield:

: 32209-47-5
1-(10H-phenothiazin-10-yl)propan-2-ol

: C₂₄H₂₃NO₃S

Guidance literature:: Multi-step reaction with 2 steps

1: Lipozyme TL IM / hexane / 24 h / 25 °C / Resolution of racemate; Enzymatic reaction

2: dmap; dicyclohexyl-carbodiimide / dichloromethane / 24 h / 20 °C

With dmap; Lipozyme TL IM; dicyclohexyl-carbodiimide; In hexane; dichloromethane;
DOI:10.3762/bjoc.10.322