10-[4-(3-Hydroxypropyl)piperazino]-8-(methylsulfonyl)-10,11-dihydrodibenzo[b,f]thiepin

Base Information

Chemical Name:10-[4-(3-Hydroxypropyl)piperazino]-8-(methylsulfonyl)-10,11-dihydrodibenzo[b,f]thiepin
CAS No.:74667-71-3
Molecular Formula:C₂₂H₂₈N₂O₃S₂
Molecular Weight:432.608
Hs Code.:
Mol file:74667-71-3.mol

Synonyms:10-[4-(3-Hydroxypropyl)piperazino]-8-(methylsulfonyl)-10,11-dihydrodibenzo[b,f]thiepin

Suppliers and Price of 10-[4-(3-Hydroxypropyl)piperazino]-8-(methylsulfonyl)-10,11-dihydrodibenzo[b,f]thiepin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 10-[4-(3-Hydroxypropyl)piperazino]-8-(methylsulfonyl)-10,11-dihydrodibenzo[b,f]thiepin

Chemical Property:

PSA：94.53000
LogP:3.79510

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 10-[4-(3-Hydroxypropyl)piperazino]-8-(methylsulfonyl)-10,11-dihydrodibenzo[b,f]thiepin

There total 1 articles about 10-[4-(3-Hydroxypropyl)piperazino]-8-(methylsulfonyl)-10,11-dihydrodibenzo[b,f]thiepin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 12.0%

: 5317-32-8
3-(1-piperazinyl)-1-propanol

: 16185-20-9
10-chloro-8-methylsulfonyl-10,11-dihydrodibenzothiepin

: 19711-55-8
2-methylsulfonyldibenzothiepin

: 74667-71-3
10-<4-(3-hydroxypropyl)piperazino>-8-methylsulfonyl-10,11-dihydrodibenzothiepin

Guidance literature:: In chloroform; for 14h; Heating;
DOI:10.1135/cccc19800529

Reference yield: 89.0%

: 74667-71-3
10-<4-(3-hydroxypropyl)piperazino>-8-methylsulfonyl-10,11-dihydrodibenzothiepin

: 74667-82-6
10-<4-(3-hydroxypropyl)piperazino>-8-methylsulfonyl-10,11-dihydrodibenzothiepin N⁴-oxide

Guidance literature:: With dihydrogen peroxide; In ethanol; for 48h; Ambient temperature;
DOI:10.1135/cccc19800529

Reference yield:

: 74667-71-3
10-<4-(3-hydroxypropyl)piperazino>-8-methylsulfonyl-10,11-dihydrodibenzothiepin

: 74667-83-7
10-<4-(3-hydroxypropyl)piperazino>-8-methylsulfonyl-10,11-dihydrodibenzothiepin N⁴,S⁵-dioxide

Guidance literature:: Multi-step reaction with 2 steps

1: methanesulfonic acid, 30percent H₂O₂ / H₂O / 40 h / Ambient temperature

2: 84 percent / 29percent H₂O₂ / ethanol; H₂O / 1) 75 deg C; 2) 48 h, room temp.

With methanesulfonic acid; dihydrogen peroxide; In ethanol; water;
DOI:10.1135/cccc19800529