tert-butyl 2-formylfuran-3-ylcarbamate

Base Information

• Chemical Name: tert-butyl 2-formylfuran-3-ylcarbamate
• CAS No.: 889088-96-4
• Molecular Formula: C₁₀H₁₃NO₄
• Molecular Weight: 211.218
• Mol file: 889088-96-4.mol

Synonyms:tert-butyl 2-formylfuran-3-ylcarbamate

Chemical Property of tert-butyl 2-formylfuran-3-ylcarbamate

Chemical Property:

• PSA: 68.54000
• LogP: 2.51210

Purity/Quality:

98%min ^*data from raw suppliers

tert-butyl2-formylfuran-3-ylcarbamate 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of tert-butyl 2-formylfuran-3-ylcarbamate

There total 2 articles about tert-butyl 2-formylfuran-3-ylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

3-bromofurfural (14757-78-9) + tert-butyl carbazate (4248-19-5) → N-(2-formyl-3-furyl)carbamic acid tert-butyl ester (889088-96-4)

Guidance literature:

With caesium carbonate; tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In toluene; at 150 ℃; for 18h; Inert atmosphere;

Reference yield: 51.0%

N-(3-furyl)carbamic acid tert-butyl ester (56267-48-2) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → N-(2-formyl-3-furyl)carbamic acid tert-butyl ester (889088-96-4)

Guidance literature:

N-(3-furyl)carbamic acid tert-butyl ester; With N,N,N,N,-tetramethylethylenediamine; tert.-butyl lithium; In tetrahydrofuran; pentane; at -90 - -40 ℃;

N,N-dimethyl-formamide; In tetrahydrofuran; pentane; at -40 - 20 ℃;

DOI:10.1055/s-2006-933132

upstream raw materials:

N-(3-furyl)carbamic acid tert-butyl ester

N,N-dimethyl-formamide

3-bromofurfural

tert-butyl carbazate