14757-78-9

Basic information

• Product Name: 3-BROMO-2-FORMYLFURAN
• Synonyms: 3-BROMO-2-FORMYLFURAN;3-BROMO-FURAN-2-CARBALDEHYDE;3-Bromo-2-furaldehyde;3-Bromofuran-2-carboxaldehyde;3-Bromo-2-formylfuran, 3-Bromo-2-furaldehyde;3-Bromo-2-furaldehyde 98%;3-Bromo-2-formylfuran, 3-Bromofuran-2-carboxaldehyde;2-Furancarboxaldehyde, 3-broMo-
• CAS NO: 14757-78-9
• Molecular Formula: C₅H₃BrO₂
• Molecular Weight: 174.98
• Product Categories: Furan&Benzofuran;Furan;Halogenated;Organohalides
• Mol File: 14757-78-9.mol
• Article Data: 22

Chemical Properties

• Boiling Point: 219.6±20.0℃ (760 Torr)
• Flash Point: 86.6±21.8℃
• Appearance: /
• Density: 1.748±0.06 g/cm3 (20 ºC 760 Torr)
• Vapor Pressure: 0.118mmHg at 25°C
• Refractive Index: 1.573
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• CAS DataBase Reference: 3-BROMO-2-FORMYLFURAN(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BROMO-2-FORMYLFURAN(14757-78-9)
• EPA Substance Registry System: 3-BROMO-2-FORMYLFURAN(14757-78-9)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22
• Hazardous Substances Data: 14757-78-9(Hazardous Substances Data)

Usage

Uses

3-Bromo-furan-2-carbaldehyde?belongs to furan derivatives and can be used as pharmaceutical intermediates.

InChI:InChI=1/C5H3BrO2/c6-4-1-2-8-5(4)3-7/h1-3H

Upstream product

• 22037-28-1 3-bromofurane 
• 68-12-2 N,N-dimethyl-formamide 
• 30544-34-4 2,3-dibromofuran 
• 4885-02-3 Dichloromethyl methyl ether 
• 38225-32-0 lithium isopropylamide 

Downstream Products

• 14757-79-0 2-formyl-furan-3-carboxylic acid 
• 688797-85-5 2-(2-phenylethenyl)furan-3-carbaldehyde 
• 908138-00-1 2-(2-phenylethenyl)-3-(2-phenylethenyl)furan 
• 817186-42-8 3-phenylethynylfuran-2-carboxaldehyde 
• 181305-77-1 2-(3-Bromo-furan-2-yl)-[1,3]dioxane 
• 98-01-1 furfural 
• 66488-00-4 3-benzylfuran-2-carbaldehyde 

Relevant articles and documents

π-Bridge Substitution in DASAs: The Subtle Equilibrium between Photochemical Improvements and Thermal Control**

Donor–acceptor Stenhouse adducts (DASAs) are playing an outstanding role as innovative and versatile photoswitches. Until now, all the efforts have been spent on modifying the donor and acceptor moieties to modulate the absorption energy and improve the c

AMIDE COMPOUND OR SALT THEREOF, AGRICULTURAL AND HORTICULTURAL MICROBICIDE COMPRISING THE COMPOUND AND THE SALT, AND METHOD FOR USING THE AGRICULTURAL AND HORTICULTURAL MICROBICIDE

An amide compound represented by the general formula [I]: or a salt thereof, an agricultural and horticultural microbicide comprising the compound or the salt as an active ingredient, and a method for using the agricultural and horticultural microbicide.

Practical nonazide synthesis of a D-amino acid oxidase inhibitor via a sequential erlenmeyer-ploechl reaction and ligand-free copper(I) amination protocol

A synthetic route to fused heterocycle 5 (R1 = Et) was developed that avoids the use of troublesome azido functionality. In this approach, 3-bromofuran aldehyde 7 was synthesized from 3-bromofuran 6 using highly regioselective formylation conditions. The crude solution of 7 was treated with hippuric acid under Erlenmeyer-Ploechl conditions to give enamide product 16, which was isolated by crystallization. Intramolecular amination/cyclization to the fused pyrrole was achieved under ligand-free Cu(I) catalysis in toluene, followed by diamine workup to remove the benzoyl protecting group and residual copper. The final product 5 (R1 = Et) was crystallized directly from the reaction mixture, providing up to 60% overall yield over five chemical steps and two isolations.