4-(3,4,5-Trimethoxyphenyl)-4-oxo-2-hydroxybutanoic acid

Base Information

• Chemical Name: 4-(3,4,5-Trimethoxyphenyl)-4-oxo-2-hydroxybutanoic acid
• CAS No.: 84386-09-4
• Molecular Formula: C13H16O7
• Molecular Weight: 284.2619
• DSSTox Substance ID: DTXSID701004662

Synonyms:4-(3,4,5-Trimethoxyphenyl)-4-oxo-2-hydroxybutanoic acid;alpha-Hydroxy-gamma-oxo-3,4,5-trimethoxybenzenebutanoic acid;Benzenebutanoic acid, alpha-hydroxy-gamma-oxo-3,4,5-trimethoxy-;84386-09-4;SCHEMBL11108485;2-hydroxy-4-oxo-4-(3,4,5-trimethoxyphenyl)butanoic acid;LZXVMAHYXAJXNC-UHFFFAOYSA-N;DTXSID701004662;LS-29349;4-(3,4,5-trimethoxyphenyl)-4-oxo-2-hydroxy butanoic acid

Chemical Property of 4-(3,4,5-Trimethoxyphenyl)-4-oxo-2-hydroxybutanoic acid

Chemical Property:

• Vapor Pressure: 2.84E-11mmHg at 25°C
• Boiling Point: 511.2°Cat760mmHg
• Flash Point: 194.1°C
• Density: 1.301g/cm³
• XLogP3: 0.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 7
• Exact Mass: 284.08960285
• Heavy Atom Count: 20
• Complexity: 330

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC(=CC(=C1OC)OC)C(=O)CC(C(=O)O)O

Technology Process of 4-(3,4,5-Trimethoxyphenyl)-4-oxo-2-hydroxybutanoic acid

There total 2 articles about 4-(3,4,5-Trimethoxyphenyl)-4-oxo-2-hydroxybutanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

methyl (3,4,5-trimethoxyphenyl) ketone (1136-86-3) + 2,2-dihydroxyacetic acid (563-96-2) → 4-(3,4,5-trimethoxyphenyl)-4-oxo-2-hydroxy butanoic acid (84386-09-4)

Guidance literature:

at 95 ℃; for 3h; under 50 Torr;

DOI:10.1016/0223-5234(88)90166-3

Reference yield:

methyl (3,4,5-trimethoxyphenyl) ketone (1136-86-3) + Glyoxilic acid (298-12-4) → 4-(3,4,5-trimethoxyphenyl)-4-oxo-2-hydroxy butanoic acid (84386-09-4)

Guidance literature:

With sodium carbonate; In water;

Reference yield: 70.0%

4-(3,4,5-trimethoxyphenyl)-4-oxo-2-hydroxy butanoic acid (84386-09-4) → (E)-4-(3,4,5-trimethoxyphenyl)-4-oxo-2-butenoic acid (84386-11-8,94201-97-5)

Guidance literature:

With hydrogenchloride; In acetic acid; for 1.5h; Heating;

DOI:10.1016/0223-5234(88)90166-3

upstream raw materials:

methyl (3,4,5-trimethoxyphenyl) ketone

2,2-dihydroxyacetic acid

Glyoxilic acid

Downstream raw materials:

(E)-4-(3,4,5-trimethoxyphenyl)-4-oxo-2-butenoic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 84386-09-4 2-hydroxy-4-oxo-4-(3,4,5-trimethoxyphenyl)butanoic acid

Send

Send

Metric Ton KG G Pound L ML

Send

Send