5'-O-(DIMETHOXYTRITYL)-2-(DIMETHYLAMINOMETHYLIDENE-AMINO)-6-(METHOXYLAMINO)PURINE-2'-DEOXYRIBOSIDE

Base Information

Chemical Name:5'-O-(DIMETHOXYTRITYL)-2-(DIMETHYLAMINOMETHYLIDENE-AMINO)-6-(METHOXYLAMINO)PURINE-2'-DEOXYRIBOSIDE
CAS No.:136986-36-2
Molecular Formula:C₃₅H₃₉N₇O₆
Molecular Weight:653.738
Hs Code.:
Mol file:136986-36-2.mol

Synonyms:5'-O-(DIMETHOXYTRITYL)-2-(DIMETHYLAMINOMETHYLIDENE-AMINO)-6-(METHOXYLAMINO)PURINE-2'-DEOXYRIBOSIDE;2-(DMF)AMINO-9-(5-O-(DMT)-BETA-D-2-DEOXYRIBOFURANOSYL)-6-(METHOXYLAMINO)PURINE

Suppliers and Price of 5'-O-(DIMETHOXYTRITYL)-2-(DIMETHYLAMINOMETHYLIDENE-AMINO)-6-(METHOXYLAMINO)PURINE-2'-DEOXYRIBOSIDE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-(DIMETHYLAMINOMETHYLIDENE)AMINO-9-(5-O-(DIMETHOXYTRITYL)-BETA-D-2-DEOXYRIBOFURANOSYL)-6-(METHOXYLAMINO)PURINE 95.00%
5MG
$ 497.43

Total 2 raw suppliers

Chemical Property of 5'-O-(DIMETHOXYTRITYL)-2-(DIMETHYLAMINOMETHYLIDENE-AMINO)-6-(METHOXYLAMINO)PURINE-2'-DEOXYRIBOSIDE

Chemical Property:

PSA：137.61000
LogP:4.76830

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

2-(DIMETHYLAMINOMETHYLIDENE)AMINO-9-(5-O-(DIMETHOXYTRITYL)-BETA-D-2-DEOXYRIBOFURANOSYL)-6-(METHOXYLAMINO)PURINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5'-O-(DIMETHOXYTRITYL)-2-(DIMETHYLAMINOMETHYLIDENE-AMINO)-6-(METHOXYLAMINO)PURINE-2'-DEOXYRIBOSIDE

There total 6 articles about 5'-O-(DIMETHOXYTRITYL)-2-(DIMETHYLAMINOMETHYLIDENE-AMINO)-6-(METHOXYLAMINO)PURINE-2'-DEOXYRIBOSIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 68045-42-1
2-Amino-9-((2R,4S,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1,9-dihydro-purin-6-one O-methyl-oxime

: 136986-36-2
N'-{9-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-6-[(Z)-methoxyimino]-6,9-dihydro-1H-purin-2-yl}-N,N-dimethyl-formamidine

Guidance literature:: Multi-step reaction with 2 steps

1: dimethylformamide / 2 h / 50 °C

2: 131 mg / pyridine / 1.5 h / Ambient temperature

With pyridine; In N,N-dimethyl-formamide;
DOI:10.1016/0008-6215(92)84156-M

Reference yield:

: 35095-93-3
2-Amino-6-chloro-9-(2-deoxy-3,5-di-O-p-toluoyl-β-D-erythro-pentofuranosyl)purine

: 136986-36-2
N'-{9-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-6-[(Z)-methoxyimino]-6,9-dihydro-1H-purin-2-yl}-N,N-dimethyl-formamidine

Guidance literature:: Multi-step reaction with 4 steps

1: 49 percent / ethanol / 4 h / 90 °C

2: NH₃ / methanol / 55 °C / overnight

3: dimethylformamide / 2 h / 50 °C

4: 131 mg / pyridine / 1.5 h / Ambient temperature

With pyridine; ammonia; In methanol; ethanol; N,N-dimethyl-formamide;
DOI:10.1016/0008-6215(92)84156-M

Reference yield:

: 136986-34-0
2-amino-9-(2-deoxy-3,5-di-O-p-toluoyl-β-D-ribofuranosyl)-6-methoxyaminopurine

: 136986-36-2
N'-{9-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-6-[(Z)-methoxyimino]-6,9-dihydro-1H-purin-2-yl}-N,N-dimethyl-formamidine

Guidance literature:: Multi-step reaction with 3 steps

1: NH₃ / methanol / 55 °C / overnight

2: dimethylformamide / 2 h / 50 °C

3: 131 mg / pyridine / 1.5 h / Ambient temperature

With pyridine; ammonia; In methanol; N,N-dimethyl-formamide;
DOI:10.1016/0008-6215(92)84156-M