5-BROMO-2-(PYRIDIN-3-YLMETHOXY)BENZALDEHYDE

Base Information

• Chemical Name: 5-BROMO-2-(PYRIDIN-3-YLMETHOXY)BENZALDEHYDE
• CAS No.: 892873-56-2
• Molecular Formula: C13H10BrNO2
• Molecular Weight: 292.132
• Hs Code.: 2933399090
• Mol file: 892873-56-2.mol

Synonyms:5-BROMO-2-(PYRIDIN-3-YLMETHOXY)BENZALDEHYDE;AKOS BBV-005058;ASISCHEM C31414;UKRORGSYN-BB BBV-005058;5-bromo-2-(3-pyridylmethoxy)benzaldehyde

Chemical Property of 5-BROMO-2-(PYRIDIN-3-YLMETHOXY)BENZALDEHYDE

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 434.221°C at 760 mmHg
• Flash Point: 216.409°C
• PSA: 39.19000
• Density: 1.496g/cm³
• LogP: 3.23560
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

5-Bromo-2-(pyridin-3-ylmethoxy)benzaldehyde 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-BROMO-2-(PYRIDIN-3-YLMETHOXY)BENZALDEHYDE

There total 2 articles about 5-BROMO-2-(PYRIDIN-3-YLMETHOXY)BENZALDEHYDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

nicotinyl chloride (3099-31-8) + 5-bromosalicyclaldehyde (1761-61-1) → 5-bromo-2-(pyridin-3-ylmethoxy)-benzaldehyde (892873-56-2)

Guidance literature:

With caesium carbonate; In N,N-dimethyl-formamide; at 100 ℃;

DOI:10.1016/j.tetlet.2006.09.059

Reference yield:

3-picolyl bromide (69966-55-8) + 5-bromosalicyclaldehyde (1761-61-1) → 5-bromo-2-(pyridin-3-ylmethoxy)-benzaldehyde (892873-56-2)

Guidance literature:

With potassium carbonate; potassium iodide; In acetone; Heating;

DOI:10.1016/j.bmcl.2006.02.060

Reference yield:

5-bromo-2-(pyridin-3-ylmethoxy)-benzaldehyde (892873-56-2) → [5-bromo-2-(pyridin-3-ylmethoxy)-phenyl]-methanol

Guidance literature:

With sodium tetrahydroborate; In tetrahydrofuran; methanol; at 0 - 20 ℃;

DOI:10.1016/j.tetlet.2006.09.059

upstream raw materials:

nicotinyl chloride

5-bromosalicyclaldehyde

3-picolyl bromide

Refernces

• 1、 Ahn, Jin Hee,Kim, Seung Jun,Park, Woul Seong,Cho, Sung Yun,Ha, Jae Du,Kim, Sung Soo,Kang, Seung Kyu,Jeong, Dae Gwin,Jung, Suk-Kyeong,Lee, Sang-Hyeup,Kim, Hwan Mook,Park, Song Kyu,Lee, Ki Ho,Lee, Chang Woo,Ryu, Seong Eon,Choi, Joong-Kwon. "Synthesis and biological evaluation of rhodanine derivatives as PRL-3 inhibitors". . p. 2996 - 2999. Retrieved 2008/09/20.