Cyclohexanecarbonitrile, 5-hydroxy-2,2-dimethyl-, (1S,5R)- (9CI)

Base Information

• Chemical Name: Cyclohexanecarbonitrile, 5-hydroxy-2,2-dimethyl-, (1S,5R)- (9CI)
• CAS No.: 623563-89-3
• Molecular Formula: C₉H₁₅NO
• Molecular Weight: 153.224
• Mol file: 623563-89-3.mol

Synonyms:Cyclohexanecarbonitrile, 5-hydroxy-2,2-dimethyl-, (1S,5R)- (9CI)

Chemical Property of Cyclohexanecarbonitrile, 5-hydroxy-2,2-dimethyl-, (1S,5R)- (9CI)

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of Cyclohexanecarbonitrile, 5-hydroxy-2,2-dimethyl-, (1S,5R)- (9CI)

There total 5 articles about Cyclohexanecarbonitrile, 5-hydroxy-2,2-dimethyl-, (1S,5R)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

2,2-dimethyl-5-oxo-cyclohexanecarbonitrile (56830-41-2) → cis-5-hydroxy-2,2-dimethylcyclohexanecarbonitrile (623563-89-3)

Guidance literature:

With sodium tetrahydroborate; In methanol; at 0 - 20 ℃; for 1.75h;

Reference yield: 55.0%

cis-3-Cyano-4,4-dimethylcyclohexyl acetate → cis-3-Cyano-4,4-dimethylcyclohexanol (623563-89-3)

Guidance literature:

With potassium carbonate; In methanol; for 16h; Ambient temperature;

Reference yield:

2,2-dimethyl-5-oxo-cyclohexanecarbonitrile (56830-41-2) → 3-Cyano-4,4-dimethylcyclohexanol (623563-89-3)

Guidance literature:

With sodium tetrahydroborate; In ethanol; at 5 ℃; for 1h;

upstream raw materials:

2,2-dimethyl-5-oxo-cyclohexanecarbonitrile

4,4-dimethylcyclohexenone