Ethyl 3-amino-4-(1-piperidinyl)benzoate

Base Information

Chemical Name:Ethyl 3-amino-4-(1-piperidinyl)benzoate
CAS No.:71254-74-5
Molecular Formula:C14H20N2O2
Molecular Weight:248.325
Hs Code.:2933399090
DSSTox Substance ID:DTXSID90384780
Wikidata:Q82177133
Mol file:71254-74-5.mol

Synonyms:Ethyl 3-amino-4-(1-piperidinyl)benzoate;71254-74-5;ethyl 3-amino-4-piperidin-1-ylbenzoate;ethyl 3-amino-4-(piperidin-1-yl)benzoate;3-Amino-4-piperidin-1-yl-benzoic acid ethyl ester;Maybridge3_003360;Oprea1_052674;SCHEMBL10049116;DTXSID90384780;NZNCMBCPAWKKSB-UHFFFAOYSA-N;HMS1440I16;CCG-41949;AKOS010560148;SB38416;IDI1_014747;ethyl3-amino-4-(piperidin-1-yl)benzoate;EN300-14584141;A1-09197;SR-01000631990-1

Suppliers and Price of Ethyl 3-amino-4-(1-piperidinyl)benzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
Ethyl 3-amino-4-(1-piperidinyl)benzoate
500mg
$ 237.00

Matrix Scientific
Ethyl 3-amino-4-(1-piperidinyl)benzoate
2.5g
$ 720.00

Crysdot
Ethyl3-amino-4-(piperidin-1-yl)benzoate 95+%
5g
$ 446.00

American Custom Chemicals Corporation
ETHYL 3-AMINO-4-(1-PIPERIDINYL)BENZOATE 95.00%
2.5G
$ 1468.50

American Custom Chemicals Corporation
ETHYL 3-AMINO-4-(1-PIPERIDINYL)BENZOATE 95.00%
500MG
$ 837.38

AK Scientific
Ethyl3-amino-4-(1-piperidinyl)benzoate
500mg
$ 369.00

A1 Biochem Labs
Ethyl3-amino-4-piperidin-1-ylbenzoate 95%
5 g
$ 700.00

Total 5 raw suppliers

Chemical Property of Ethyl 3-amino-4-(1-piperidinyl)benzoate

Chemical Property:

Melting Point:84 °C(Solv: ligroine (8032-32-4))
Boiling Point:425.2±35.0 °C(Predicted)
PKA:6.31±0.11(Predicted)
PSA：55.56000
Density:1.137±0.06 g/cm3(Predicted)
LogP:3.08200
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:248.152477885
Heavy Atom Count:18
Complexity:277

Purity/Quality:

98%min ^*data from raw suppliers

Ethyl 3-amino-4-(1-piperidinyl)benzoate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)C1=CC(=C(C=C1)N2CCCCC2)N

Technology Process of Ethyl 3-amino-4-(1-piperidinyl)benzoate

There total 4 articles about Ethyl 3-amino-4-(1-piperidinyl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 71254-72-3
ethyl 3-nitro-4-piperidin-1-ylbenzoate

: 71254-74-5
ethyl 3-amino-4-piperidin-1-ylbenzoate

Guidance literature:: With 5%-palladium/activated carbon; hydrogen; In methanol; at 20 ℃;

Reference yield:

: 367-80-6
ethyl 4-fluoro-3-nitrobenzoate

: 71254-74-5
ethyl 3-amino-4-piperidin-1-ylbenzoate

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / ethanol / 2 h / 20 °C / Cooling with ice

2: 5%-palladium/activated carbon; hydrogen / methanol / 20 °C

With 5%-palladium/activated carbon; hydrogen; triethylamine; In methanol; ethanol;

Reference yield:

: 453-71-4
3-nitro-4-fluorobenzoic acid

: 71254-74-5
ethyl 3-amino-4-piperidin-1-ylbenzoate

Guidance literature:: Multi-step reaction with 3 steps

1: sulfuric acid / 8 h / Reflux

2: triethylamine / ethanol / 2 h / 20 °C / Cooling with ice

3: 5%-palladium/activated carbon; hydrogen / methanol / 20 °C

With sulfuric acid; 5%-palladium/activated carbon; hydrogen; triethylamine; In methanol; ethanol;