Docosahexaenoyl Ethanolamide-d4

Base Information

• Chemical Name: Docosahexaenoyl Ethanolamide-d4
• CAS No.: 946524-43-2
• Molecular Formula: C₂₄H₃₇NO₂
• Molecular Weight: 375.532
• Mol file: 946524-43-2.mol

Synonyms:Docosahexaenoyl Ethanolamide-d4;SynaptaMide-d4

Chemical Property of Docosahexaenoyl Ethanolamide-d4

Chemical Property:

• PSA: 52.82000
• LogP: 6.41310

Purity/Quality:

99% ^*data from raw suppliers

Synaptamide-d4 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Docosahexaenoyl Ethanolamide-d4

There total 2 articles about Docosahexaenoyl Ethanolamide-d4 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

docosahexaenoic acid (6217-54-5) + 2-amino(2H4)ethan-1-ol (85047-08-1) → 4,7,10,13,16,19-docosahexaenoyl ethanolamide-d4 (946524-43-2)

Guidance literature:

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In acetonitrile; at 20 ℃;

DOI:10.1021/ac0624086

Reference yield:

2-amino(2H4)ethan-1-ol (85047-08-1) + (4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoyl chloride (98776-99-9,158754-21-3) → 4,7,10,13,16,19-docosahexaenoyl ethanolamide-d4 (946524-43-2)

Guidance literature:

In dichloromethane; for 0.333333h; Cooling with ice;

DOI:10.1111/jnc.12255

upstream raw materials:

docosahexaenoic acid

2-amino(²H₄)ethan-1-ol

(4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoyl chloride

Refernces

• 1、 Williams, John,Wood, JodiAnne,Pandarinathan, Lakshmipathi,Karanian, David A.,Bahr, Ben A.,Vouros, Paul,Makriyannis, Alexandros. "Quantitative method for the profiling of the endocannabinoid metabolome by LC-atmospheric pressure chemical ionization-MS". . p. 5582 - 5593. Retrieved 2008/03/12.