2-Amino-N-ethyl-N-phenylbenzamide

Base Information

• Chemical Name: 2-Amino-N-ethyl-N-phenylbenzamide
• CAS No.: 29094-86-8
• Molecular Formula: C15H16N2O
• Molecular Weight: 240.305
• Hs Code.: 2924299090
• ChEMBL ID: CHEMBL264419
• DSSTox Substance ID: DTXSID20586396
• Wikidata: Q82478515
• Mol file: 29094-86-8.mol

Synonyms:2-Amino-N-ethyl-N-phenylbenzamide;29094-86-8;CHEMBL264419;DTXSID20586396;STL067529;AKOS000146863;MCULE-4315431027;CS-0333339

Chemical Property of 2-Amino-N-ethyl-N-phenylbenzamide

Chemical Property:

• PSA: 46.33000
• LogP: 3.51670
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 240.126263138
• Heavy Atom Count: 18
• Complexity: 274

Purity/Quality:

98%min ^*data from raw suppliers

2-Amino-N-ethyl-N-phenylbenzamide ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

Useful:

• Canonical SMILES: CCN(C1=CC=CC=C1)C(=O)C2=CC=CC=C2N

Technology Process of 2-Amino-N-ethyl-N-phenylbenzamide

There total 5 articles about 2-Amino-N-ethyl-N-phenylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

N-ethyl-2-nitro-N-(phenyl)benzamide (328259-21-8) → anthranilic acid-(N-ethyl-anilide) (29094-86-8)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethyl acetate; under 750.075 Torr;

DOI:10.1021/jm701191z

Reference yield:

isatoic anhydride (118-48-9) + N-ethyl-N-phenylamine (103-69-5) → anthranilic acid-(N-ethyl-anilide) (29094-86-8)

Guidance literature:

at 120 ℃;

DOI:10.1021/jo01183a007

Reference yield:

N-ethyl-N-phenylamine (103-69-5) → anthranilic acid-(N-ethyl-anilide) (29094-86-8)

Guidance literature:

Multi-step reaction with 2 steps

2: platinum; ethanol / Hydrogenation

With ethanol; platinum;

upstream raw materials:

isatoic anhydride

N-ethyl-N-phenylamine

N-ethyl-2-nitro-N-(phenyl)benzamide

2-nitrobenzyl chloride

Refernces