N-(6-Fluoro-5-iodopyridin-2-yl)acetamide

Base Information

Chemical Name:N-(6-Fluoro-5-iodopyridin-2-yl)acetamide
CAS No.:884660-46-2
Molecular Formula:C₇H₆FIN₂O
Molecular Weight:280.04
Hs Code.:
DSSTox Substance ID:DTXSID00468580
Wikidata:Q82295849
Mol file:884660-46-2.mol

Synonyms:N-(6-Fluoro-5-iodopyridin-2-yl)acetamide;884660-46-2;N-(6-Fluoro-5-iodo-pyridin-2-yl)-acetamide;C7H6FIN2O;SCHEMBL16631609;DTXSID00468580;AKOS004114847;AS-83626;CS-0311893;Acetamide, N-(6-fluoro-5-iodo-2-pyridinyl)-

Suppliers and Price of N-(6-Fluoro-5-iodopyridin-2-yl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
N-(6-Fluoro-5-iodopyridin-2-yl)acetamide 95+%
1g
$ 406.00

Chemenu
N-(6-fluoro-5-iodopyridin-2-yl)acetamide 95%
1g
$ 380.00

American Custom Chemicals Corporation
N-(6-FLUORO-5-IODO-PYRIDIN-2-YL)-ACETAMIDE 95.00%
5MG
$ 495.58

Alichem
N-(6-Fluoro-5-iodopyridin-2-yl)acetamide
1g
$ 334.56

Total 10 raw suppliers

Chemical Property of N-(6-Fluoro-5-iodopyridin-2-yl)acetamide

Chemical Property:

PSA：45.48000
LogP:2.43320
Storage Temp.:2-8°C
XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:279.95089
Heavy Atom Count:12
Complexity:179

Purity/Quality:

97% ^*data from raw suppliers

N-(6-Fluoro-5-iodopyridin-2-yl)acetamide 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC1=NC(=C(C=C1)I)F

Technology Process of N-(6-Fluoro-5-iodopyridin-2-yl)acetamide

There total 3 articles about N-(6-Fluoro-5-iodopyridin-2-yl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 884660-45-1
N-(6-amino-5-iodopyridin-2-yl)acetamide

: 884660-46-2
N-(6-fluoro-5-iodopyridin-2-yl)acetamide

Guidance literature:: With tetrafluoroboric acid; sodium nitrite; In water; at -5 ℃; for 2h;
DOI:10.1021/jo060066y

Reference yield:

: 141-86-6
2.6-diaminopyridine

: 884660-46-2
N-(6-fluoro-5-iodopyridin-2-yl)acetamide

Guidance literature:: Multi-step reaction with 3 steps

1: 60 percent / AcOH; H₂SO₄; I₂ / periodic acid / H₂O / 5 h / 55 °C

2: 85 percent / pyridine / 12 h / 20 °C

3: 64 percent / HBF₄; NaNO₂ / H₂O / 2 h / -5 °C

With pyridine; tetrafluoroboric acid; sulfuric acid; iodine; acetic acid; sodium nitrite; periodic acid; In water;
DOI:10.1021/jo060066y

Reference yield:

: 856851-34-8
2,6-diamino-3-iodopyridine

: 884660-46-2
N-(6-fluoro-5-iodopyridin-2-yl)acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / pyridine / 12 h / 20 °C

2: 64 percent / HBF₄; NaNO₂ / H₂O / 2 h / -5 °C

With pyridine; tetrafluoroboric acid; sodium nitrite; In water;
DOI:10.1021/jo060066y