1-0-Octadecyl 2-0-acetyl sn-glycero-3-phosphorylcholine

Base Information

Chemical Name:1-0-Octadecyl 2-0-acetyl sn-glycero-3-phosphorylcholine
CAS No.:85733-91-1
Molecular Formula:C28H58NO7P
Molecular Weight:551.7364
Hs Code.:
DSSTox Substance ID:DTXSID501110671
ChEMBL ID:CHEMBL12852
Mol file:85733-91-1.mol

Synonyms:1-0-octadecyl 2-0-acetyl sn-glycero-3-phosphorylcholine;1-0-octadecyl 2-0-acetyl sn-glycero-3-phosphorylcholine, (R)-isomer;C18-PAF;octadecyl PAF;octadecyl-AGPC;octadecyl-PAF-acether

Suppliers and Price of 1-0-Octadecyl 2-0-acetyl sn-glycero-3-phosphorylcholine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-ORTHO-OCTADECYL-2-ORTHO-ACETYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE 95.00%
5MG
$ 496.14

Total 0 raw suppliers

Chemical Property of 1-0-Octadecyl 2-0-acetyl sn-glycero-3-phosphorylcholine

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
PSA：103.93000
Density:g/cm³
LogP:7.47420
XLogP3:7.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:28
Exact Mass:551.39509019
Heavy Atom Count:37
Complexity:575

Purity/Quality:: 1-ORTHO-OCTADECYL-2-ORTHO-ACETYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCCCCCCCCCCCCCCCCCOCC(COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)C

Technology Process of 1-0-Octadecyl 2-0-acetyl sn-glycero-3-phosphorylcholine

There total 12 articles about 1-0-Octadecyl 2-0-acetyl sn-glycero-3-phosphorylcholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 544-62-7
batyl alcohol

: 85733-91-1
1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine

Guidance literature:: Multi-step reaction with 5 steps

1: Et₃N / toluene / 3 h / Heating

2: pyridine

3: H₂, CaCO₃ / 10percent Pd/C / CHCl₃ / 18 h / 40 °C / 1034.3 Torr

4: 1.) Et₃N, 2.) Et₃N, water / 1.) diethyl ether, RT, 5 h, 2.) diethyl ether, reflux, 2 h

5: CHCl₃; propan-2-ol; dimethylformamide / 12 h / 50 °C

With pyridine; water; hydrogen; triethylamine; calcium carbonate; palladium on activated charcoal; In chloroform; N,N-dimethyl-formamide; isopropyl alcohol; toluene;
DOI:10.1021/jm00388a008

Reference yield:

: 86334-56-7
1-octadecyloxy-3-trityloxy-propan-2-ol

: 85733-91-1
1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine

Guidance literature:: Multi-step reaction with 4 steps

1: pyridine

2: H₂, CaCO₃ / 10percent Pd/C / CHCl₃ / 18 h / 40 °C / 1034.3 Torr

3: 1.) Et₃N, 2.) Et₃N, water / 1.) diethyl ether, RT, 5 h, 2.) diethyl ether, reflux, 2 h

4: CHCl₃; propan-2-ol; dimethylformamide / 12 h / 50 °C

With pyridine; water; hydrogen; triethylamine; calcium carbonate; palladium on activated charcoal; In chloroform; N,N-dimethyl-formamide; isopropyl alcohol;
DOI:10.1021/jm00388a008

Reference yield:

: 89496-74-2
Acetic acid 1-octadecyloxymethyl-2-trityloxy-ethyl ester

: 85733-91-1
1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine

Guidance literature:: Multi-step reaction with 3 steps

1: H₂, CaCO₃ / 10percent Pd/C / CHCl₃ / 18 h / 40 °C / 1034.3 Torr

2: 1.) Et₃N, 2.) Et₃N, water / 1.) diethyl ether, RT, 5 h, 2.) diethyl ether, reflux, 2 h

3: CHCl₃; propan-2-ol; dimethylformamide / 12 h / 50 °C

With water; hydrogen; triethylamine; calcium carbonate; palladium on activated charcoal; In chloroform; N,N-dimethyl-formamide; isopropyl alcohol;
DOI:10.1021/jm00388a008