86334-56-7

Basic information

• Product Name: 1-O-OCTADECYL-3-O-TRITYL-RAC-GLYCEROL
• Synonyms: 1-O-OCTADECYL-3-O-TRITYL-RAC-GLYCEROL
• CAS NO: 86334-56-7
• Molecular Formula: C₄₀H₅₈O₃
• Molecular Weight: 586.89
• Mol File: 86334-56-7.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-O-OCTADECYL-3-O-TRITYL-RAC-GLYCEROL(CAS DataBase Reference)
• NIST Chemistry Reference: 1-O-OCTADECYL-3-O-TRITYL-RAC-GLYCEROL(86334-56-7)
• EPA Substance Registry System: 1-O-OCTADECYL-3-O-TRITYL-RAC-GLYCEROL(86334-56-7)

Safety Data

• Hazardous Substances Data: 86334-56-7(Hazardous Substances Data)

Usage

Molecular structure

A complex compound consisting of an octadecyl group and a trityl group attached to a racemic glycerol molecule.

Usage as a lipid

Commonly used in scientific and industrial applications, such as a precursor for the synthesis of lipids with specific properties for pharmaceutical and cosmetic products.

Drug delivery systems

Utilized in research and development for creating drug delivery systems due to its unique properties.

Membrane biology and function

Aids in the study of membrane biology and function, providing insights into cellular processes.

Potential applications in nanotechnology

The compound's unique chemical and physical properties make it a candidate for use in nanotechnology.

Potential applications in biotechnology

Its distinctive structure and properties may also have applications in the field of biotechnology.

Upstream product

• 544-62-7 batyl alcohol 
• 76-83-5 trityl chloride 
• 112-92-5 1-octadecanol 
• 16725-43-2 4-(n-octadecyloxymethyl)-2,2-dimethyl-1,3-dioxolane 
• 25580-78-3 1-[(prop-2'-en-1'-yl)oxy]octadecane 
• 31081-59-1 1-octadecyl methanesulfonate 
• 3386-32-1 n-octadecyl p-toluenesulfonate 

Downstream Products

• 97152-45-9 1-octadecyloxy-2-palmitoyloxy-3-trityloxy-propane 
• 106972-47-8 C₄₇H₆₄O₃ 
• 104494-55-5 2-benzoyl-3-octadecyl-1-tritylglycerol 
• 63326-69-2 1-O-Octadecyl-2-O-p-toluenesulfonyl-3-O-trityl-glycerol 
• 89078-77-3 3-Octadecyl-2-morpholinocarbonyl-1-tritylglycerol 
• 84337-43-9 2-methoxy-3-octadecyloxy-1-propanol 
• 38169-74-3 1-O-Octadecyl-3-O-trityl-sn-glycerin 
• 6076-32-0 3-O-Octadecyl-1-O-trityl-sn-glycerin 
• 51134-45-3 2-(benzyloxy)-3-(octadecyloxy)propyl 2-bromoethyl phosphate 
• 85733-91-1 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine 
• 72490-82-5 2-hydroxy-3-(octadecyloxy)propyl 2-(trimethylammonio)ethyl phosphate 
• 43043-61-4 C₃₃H₆₂NO₆P 
• 86008-21-1 2-(benzyloxy)-3-(octadecyloxy)-1-propanol 
• 103383-67-1 1-β-D-arabinofuranosylcytosine 5'-diphosphate-rac-1-O-octadecyl-2-O-palmitoylglycerol 

Relevant articles and documents

Synthesis of phospholipid conjugates of N1-(2-furanidyl)-N3-(2-hydroxyethyl)-5-fluorouracil

The synthesis of phospholipid conjugates of N′-(2-furanidyl)-N3-(2-hydroxyethyl)-5-fluorouracil is reported. The strategy for the synthesis is using hexaethylphosphorous triamide, activated by a catalytic amount of iodine, as the phosphorylatin

Sterol-modified phospholipids: Cholesterol and phospholipid chimeras with improved biomembrane properties

We synthesized a family of sterol-modified glycerophospholipids (SML) in which the sn-1 or sn-2 position is covalently attached to cholesterol and the alternative position contains an aliphatic chain. The SML were used to explore how anchoring cholesterol to a phospholipid affects cholesterol behavior in a bilayer. Notably, cholesterol in the SML retains the membrane condensing properties of free cholesterol regardless of the chemistry or position of its attachment to the glycerol moiety of the phospholipid. SMLs by themselves formed liposomes upon hydration and in mixtures between an SML and diacylglycerophospholipids (C14 to C18 chain length) the thermotropic phase transition is eliminated at the SML equivalent of about 30 mol % free cholesterol. Osmotic-induced contents leakage from SML (C14-C18) liposomes depends upon the linkage and position of cholesterol but in general is similar to that observed in 3/2 diacylphosphatidylcholine/cholesterol (mole ratio) liposomes. SML liposomes are exceptionally resistant to contents release in the presence of serum at 37°C. This is probably due to the fact that SML exchange between bilayers is more than 100 fold less than the exchange rate of free cholesterol in the same conditions. Importantly, SML liposomes containing doxorubicin are as effective in treating the murine C26 colon carcinoma as Doxil, a commercial liposome doxorubicin formulation. SMLs stabilize bilayers but do not exchange and hence provide a new tool for biophysical studies on membranes. They may improve liposomal drug delivery in organs predisposed to the extraction of free cholesterol from bilayers, such as the skin, lung, or blood.

Preparation of N-het-substituted glycerophosphoethanolamines as antitumor and anti-inflammatory agents.

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