Cyclopentane-1,2-diamine hydrochloride

Base Information

• Chemical Name: Cyclopentane-1,2-diamine hydrochloride
• CAS No.: 99363-25-4
• Molecular Formula: C₅H₁₂N₂*2ClH
• Molecular Weight: 173.086
• DSSTox Substance ID: DTXSID90701776
• Mol file: 99363-25-4.mol

Synonyms:DTXSID90701776;Cyclopentane-1,2-diamine hydrochloride;CS-0197792;Cyclopentane-1,2-diamine--hydrogen chloride (1/1)

Chemical Property of Cyclopentane-1,2-diamine hydrochloride

Chemical Property:

• PSA: 52.04000
• LogP: 2.02750
• Storage Temp.: Inert atmosphere,Room Temperature
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 136.0767261
• Heavy Atom Count: 8
• Complexity: 55.1

Purity/Quality:

99% ^*data from raw suppliers

trans-Cyclopentane-1,2-diaminedihydrochloride 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC(C(C1)N)N.Cl

Technology Process of Cyclopentane-1,2-diamine hydrochloride

There total 5 articles about Cyclopentane-1,2-diamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

trans-1,2-di(tert-butoxycarbonylamino)cyclopentane → rac-(1R,2R)-cyclopentane-1,2-diamine dihydrochloride (99363-25-4,118634-23-4,121187-63-1,477873-22-6)

Guidance literature:

With hydrogenchloride; In ethanol; water; for 3h; Heating;

DOI:10.1080/00397910008087424

Reference yield: 91.0%

(+/-)-trans-1,2-diazido-cyclopentane → rac-(1R,2R)-cyclopentane-1,2-diamine dihydrochloride (99363-25-4,118634-23-4,121187-63-1,477873-22-6)

Guidance literature:

With hydrogenchloride; hydrogen; palladium dihydroxide; In methanol; water; at 20 ℃; for 8h; under 760 Torr;

DOI:10.1016/S0040-4020(01)01198-X

Reference yield: 62.0%

rac-1,2-cyclopentanediyl bis(methanesulfonate) → rac-(1R,2R)-cyclopentane-1,2-diamine dihydrochloride (99363-25-4,118634-23-4,121187-63-1,477873-22-6)

Guidance literature:

rac-1,2-cyclopentanediyl bis(methanesulfonate); With sodium azide; In N,N-dimethyl-formamide; at 100 ℃; for 4h;

With hydrogenchloride; hydrogen; In ethanol; for 26h; under 3000.24 Torr;

DOI:10.1002/1099-0682(200109)2001:10<2525::AID-EJIC2525>3.0.CO;2-Z

upstream raw materials:

trans-cyclopentane-1,2-diol

Refernces

• 1、 Kuppert, Dirk,Sander, Juergen,Roth, Christian,Woerle, Michael,Weyhermueller, Thomas,Reiss, Guido J.,Schilde, Uwe,Mueller, Iris,Hegetschweiler, Kaspar. "The coordination chemistry of cis-3,4-diaminopyrrolidine and related polyamines". . p. 2525 - 2542. Retrieved 2007/10/03.