ETHYL PYRUVATE-3-FORMYLAMINO-4-METHOXYPHENYLHYDRAZONE

Base Information

• Chemical Name: ETHYL PYRUVATE-3-FORMYLAMINO-4-METHOXYPHENYLHYDRAZONE
• CAS No.: 107575-59-7
• Molecular Formula: C13H17N3O4
• Molecular Weight: 279.296
• Mol file: 107575-59-7.mol

Synonyms:ETHYL PYRUVATE-3-FORMYLAMINO-4-METHOXYPHENYLHYDRAZONE;2-[2-[3-(ForMylaMino)-4-Methoxyphenyl]hydrazinylidene]propanoic Acid Ethyl Ester

Chemical Property of ETHYL PYRUVATE-3-FORMYLAMINO-4-METHOXYPHENYLHYDRAZONE

Chemical Property:

• PSA: 92.51000
• LogP: 2.33690
• Storage Temp.: Refrigerator
• Solubility.: DMSO

Purity/Quality:

97% ^*data from raw suppliers

Ethyl pyruvate-3-formylamino-4-methoxyphenylhydrazone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: Ethyl Pyruvate-3-formylamino-4-methoxyphenylhydrazone (cas# 107575-59-7) is a compound useful in organic synthesis.

Technology Process of ETHYL PYRUVATE-3-FORMYLAMINO-4-METHOXYPHENYLHYDRAZONE

There total 4 articles about ETHYL PYRUVATE-3-FORMYLAMINO-4-METHOXYPHENYLHYDRAZONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.6%

2-acetylpropanoic acid ethyl ester (609-14-3) + N-(5-amino-2-methoxylphenyl)formamide (78939-34-1) → ethyl pyruvate 3-formamido-4-methoxyphenyl-hydrazone (107575-59-7)

Guidance literature:

N-(5-amino-2-methoxylphenyl)formamide; With hydrogenchloride; In water; at -20 ℃; for 0.5h;

With sodium nitrite; In ethanol; water; at -15 ℃; for 0.833333h;

2-acetylpropanoic acid ethyl ester; Further stages;

Reference yield:

2-acetylpropanoic acid ethyl ester (609-14-3) + BF4(1-)*C8H9N3O2*H(1+) → ethyl pyruvate 3-formamido-4-methoxyphenyl-hydrazone (107575-59-7)

Guidance literature:

With sodium acetate; In ethanol; water; at -8 ℃; for 22.2h;

Reference yield:

3-amino-4-methoxynitrobenzene (99-59-2) → ethyl pyruvate 3-formamido-4-methoxyphenyl-hydrazone (107575-59-7)

Guidance literature:

Multi-step reaction with 3 steps

1.1: 1-(3-sulfopropyl)pyridinium phosphotungstate / 0.08 h / 70 °C

2.1: sodium tetrahydroborate / N,N-dimethyl-formamide / 120 h / 70 °C

3.1: hydrogenchloride / water / 0.5 h / -20 °C

3.2: 0.83 h / -15 °C

With hydrogenchloride; sodium tetrahydroborate; 1-(3-sulfopropyl)pyridinium phosphotungstate; In water; N,N-dimethyl-formamide;

upstream raw materials:

2-acetylpropanoic acid ethyl ester

N-(5-amino-2-methoxylphenyl)formamide

3-amino-4-methoxynitrobenzene

N-(2-methoxyl-5-nitrophenyl)formamide

Downstream raw materials:

6-(Formylamino)-5-methoxyindol-2-carbonsaeure-ethylester

4,5-Dihydro-4,5-dioxo-1H-pyrrolo<2,3-f>chinolin-2,7,9-tricarbonsaeure-(2-ethyl)(7,9-dimethyl)ester

pyrroloquinoline quinone

6-amino-5-methoxy-2-ethoxycarbonylindole