7-Chloro-8-fluoro-2-phenylquinolin-4(1H)-one

Base Information

Chemical Name:7-Chloro-8-fluoro-2-phenylquinolin-4(1H)-one
CAS No.:867165-00-2
Molecular Formula:C15H9ClFNO
Molecular Weight:273.694
Hs Code.:
DSSTox Substance ID:DTXSID90656277
Wikidata:Q82570859
Mol file:867165-00-2.mol

Synonyms:7-Chloro-8-fluoro-2-phenylquinolin-4(1H)-one;867165-00-2;7-chloro-8-fluoro-2-phenyl-1H-quinolin-4-one;SCHEMBL401897;DTXSID90656277;HZUOLYGWXKPPNY-UHFFFAOYSA-N;AKOS005903593;SB69137

Suppliers and Price of 7-Chloro-8-fluoro-2-phenylquinolin-4(1H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
7-Chloro-8-fluoro-2-phenylquinolin-4(1H)-one 95+%
1g
$ 975.00

Matrix Scientific
7-Chloro-8-fluoro-2-phenylquinolin-4(1H)-one 95+%
250mg
$ 435.00

Crysdot
7-Chloro-8-fluoro-2-phenylquinolin-4(1H)-one 95+%
1g
$ 455.00

Chemenu
7-Chloro-8-fluoro-2-phenylquinolin-4(1H)-one 95%
1g
$ 430.00

American Custom Chemicals Corporation
7-CHLORO-8-FLUORO-2-PHENYLQUINOLIN-4(1H)-ONE 95.00%
5MG
$ 502.12

Alichem
7-Chloro-8-fluoro-2-phenylquinolin-4(1H)-one
1g
$ 390.60

AK Scientific
7-Chloro-8-fluoro-2-phenylquinolin-4(1H)-one
1g
$ 1366.00

Total 3 raw suppliers

Chemical Property of 7-Chloro-8-fluoro-2-phenylquinolin-4(1H)-one

Chemical Property:

PSA：32.86000
LogP:3.98760
Storage Temp.:2-8°C
XLogP3:3.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:273.0356698
Heavy Atom Count:19
Complexity:392

Purity/Quality:

95+% ^*data from raw suppliers

7-Chloro-8-fluoro-2-phenylquinolin-4(1H)-one 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=CC(=O)C3=C(N2)C(=C(C=C3)Cl)F

Technology Process of 7-Chloro-8-fluoro-2-phenylquinolin-4(1H)-one

There total 2 articles about 7-Chloro-8-fluoro-2-phenylquinolin-4(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 867165-02-4
3-(3-chloro-2-fluoro-phenylamino)-3-phenyl-acrylic acid ethyl ester

: 867165-00-2
7-chloro-8-fluoro-2-phenyl-1H-quinolin-4-one

Guidance literature:: With PPA; at 175 ℃; for 0.666667h;

Reference yield:

: 94-02-0
ethyl 3-oxo-3-phenylpropionate

: 867165-00-2
7-chloro-8-fluoro-2-phenyl-1H-quinolin-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: toluene-4-sulfonic acid / toluene / 3 h / Reflux; Dean-Stark apparatus

2: polyphosphoric acid / 0.67 h / 175 °C / Inert atmosphere

With toluene-4-sulfonic acid; In toluene;