1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-3-(tert-butoxycarbonyl)imidazolidine-2-carboxylic acid

Base Information

• Chemical Name: 1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-3-(tert-butoxycarbonyl)imidazolidine-2-carboxylic acid
• CAS No.: 207129-12-2
• Molecular Formula: C₂₄H₂₆N₂O₆
• Molecular Weight: 438.48
• Hs Code.: 29333990
• DSSTox Substance ID: DTXSID20373263
• Nikkaji Number: J956.119F
• Mol file: 207129-12-2.mol

Synonyms:207129-12-2;1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-3-(tert-butoxycarbonyl)imidazolidine-2-carboxylic acid;Fmoc-(R,S)-Boc-imidazolidine-2-carboxylic acid;(r,s)-n-fmoc-n'-boc-imidazolidine-2-carboxylic acid;1-(9H-fluoren-9-ylmethoxycarbonyl)-3-[(2-methylpropan-2-yl)oxycarbonyl]imidazolidine-2-carboxylic acid;DTXSID20373263;MFCD01321020;AKOS027326354;AS-74472;CS-0324025;W13576;(R,S)-N-Fmoc-N'-Boc-imidazolidine-2-carboxylic acid, AldrichCPR;Imidazolidine-1,2,3-tricarboxylic acid 1-tert-butyl 3-(9H-fluorene-9-ylmethyl) ester;1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-3-(tert-butoxycarbonyl)imidazolidine-2-carboxylicacid;1-[(tert-butoxy)carbonyl]-3-[(9H-fluoren-9-ylmethoxy)carbonyl]imidazolidine-2-carboxylic acid;1-[(tert-butoxy)carbonyl]-3-{[(9H-fluoren-9-yl)methoxy]carbonyl}imidazolidine-2-carboxylate

Chemical Property of 1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-3-(tert-butoxycarbonyl)imidazolidine-2-carboxylic acid

Chemical Property:

• PSA: 96.38000
• LogP: 3.77470
• Storage Temp.: Store at -15°C
• XLogP3: 3.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 6
• Exact Mass: 438.17908655
• Heavy Atom Count: 32
• Complexity: 713

Purity/Quality:

97% ^*data from raw suppliers

(R,S)-N-Fmoc-n''-boc-imidazolidine-2-carboxylicacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C)OC(=O)N1CCN(C1C(=O)O)C(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24
• Uses: (R,S)-N-Fmoc-n''-boc-imidazolidine-2-carboxylic acid is an intermediate used in the preparation of new proline analog, N-protected imidazolidinecarboxylate.

Technology Process of 1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-3-(tert-butoxycarbonyl)imidazolidine-2-carboxylic acid

There total 1 articles about 1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-3-(tert-butoxycarbonyl)imidazolidine-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

N-(tert-butyloxycarbonyl)-N'-(9H-fluoren-9-ylmethoxycarbonyl)-1,2-diaminoethane (166410-28-2) + Glyoxilic acid (298-12-4) → N-Boc-N'-Fmoc-imidazolidine-2-carboxylic acid (207129-12-2)

Guidance literature:

In acetic acid; at 60 ℃;

DOI:10.1016/S0040-4039(98)00262-7

upstream raw materials:

N-(tert-butyloxycarbonyl)-N'-(9H-fluoren-9-ylmethoxycarbonyl)-1,2-diaminoethane

Glyoxilic acid