4-(Chloromethyl)-1-methylpiperidine

Base Information

Chemical Name:4-(Chloromethyl)-1-methylpiperidine
CAS No.:52694-51-6
Molecular Formula:C7H14ClN
Molecular Weight:147.648
Hs Code.:2933399090
DSSTox Substance ID:DTXSID70566986
Mol file:52694-51-6.mol

Synonyms:4-(chloromethyl)-1-methylpiperidine;52694-51-6;4-Chloromethyl-1-methyl-piperidine;SCHEMBL1966713;DTXSID70566986;AKOS005207214;SB41630;CS-0453347;EN300-103129;A923385

Suppliers and Price of 4-(Chloromethyl)-1-methylpiperidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
4-(Chloromethyl)-1-methylpiperidine 95+%
1g
$ 852.00

AccelPharmtech
4-(chloromethyl)-1-methyl-Piperidine 97.00%
25G
$ 3120.00

AccelPharmtech
4-(chloromethyl)-1-methyl-Piperidine 97.00%
5G
$ 1700.00

AccelPharmtech
4-(chloromethyl)-1-methyl-Piperidine 97.00%
1G
$ 1530.00

Total 4 raw suppliers

Chemical Property of 4-(Chloromethyl)-1-methylpiperidine

Chemical Property:

Boiling Point:55-60 °C(Press: 0.05 Torr)
PKA:8.97±0.10(Predicted)
PSA：3.24000
Density:0.984±0.06 g/cm3(Predicted)
LogP:1.50490
XLogP3:1.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:147.0814771
Heavy Atom Count:9
Complexity:77

Purity/Quality:

97% ^*data from raw suppliers

4-(Chloromethyl)-1-methylpiperidine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCC(CC1)CCl

Technology Process of 4-(Chloromethyl)-1-methylpiperidine

There total 2 articles about 4-(Chloromethyl)-1-methylpiperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 20691-89-8
1-methyl-4-piperidinemethanol

: 52694-51-6
4-(chloromethyl)-1-methylpiperidine

Guidance literature:: With thionyl chloride; for 2h; Heating / reflux;

Reference yield:

: 52694-51-6
4-(chloromethyl)-1-methylpiperidine

Guidance literature:: Aus N-Methyl-4-hydroxymethyl-piperidin;

Reference yield: 77.0%

: 70547-26-1
2-phenyl-4-hydroxy-5-methylthiazole

: 52694-51-6
4-(chloromethyl)-1-methylpiperidine

: 5-methyl-4-((1-methylpiperidin-4-yl)methoxy)-2-phenylthiazole

Guidance literature:: 2-phenyl-4-hydroxy-5-methylthiazole; With potassium carbonate; In N,N-dimethyl-formamide; at 60 ℃; for 0.5h;

4-(chloromethyl)-1-methylpiperidine; With potassium iodide; In N,N-dimethyl-formamide; at 60 ℃; for 8h;
DOI:10.1016/j.bmc.2018.06.028