3-Bromo-4-[(4-methylpiperazin-1-yl)methyl]benzoic acid

Base Information

Chemical Name:3-Bromo-4-[(4-methylpiperazin-1-yl)methyl]benzoic acid
CAS No.:765269-29-2
Molecular Formula:C₁₃H₁₇BrN₂O₂
Molecular Weight:313.194
Hs Code.:2933599090
Mol file:765269-29-2.mol

Synonyms:3-Bromo-4-[(4-methylpiperazin-1-yl)methyl]benzoic acid;3-BROMO-4-[(4-METHYL-1-PIPERAZINYL)METHYL]BENZOIC ACID

Suppliers and Price of 3-Bromo-4-[(4-methylpiperazin-1-yl)methyl]benzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynChem
3-bromo-4-((4-methylpiperazin-1-yl)methyl)benzoic acid 95+%
500 mg
$ 300.00

American Custom Chemicals Corporation
3-BROMO-4-((4-METHYLPIPERAZIN-1-YL)METHYL)BENZOIC ACID 95.00%
1G
$ 1379.70

American Custom Chemicals Corporation
3-BROMO-4-((4-METHYLPIPERAZIN-1-YL)METHYL)BENZOIC ACID 95.00%
500MG
$ 909.56

Total 9 raw suppliers

Chemical Property of 3-Bromo-4-[(4-methylpiperazin-1-yl)methyl]benzoic acid

Chemical Property:

Vapor Pressure:7.94E-08mmHg at 25°C
Boiling Point:420.6°C at 760 mmHg
PKA:3.92±0.10(Predicted)
Flash Point:208.2°C
PSA：43.78000
Density:1.452g/cm³
LogP:1.77050

Purity/Quality:

97% ^*data from raw suppliers

3-bromo-4-((4-methylpiperazin-1-yl)methyl)benzoic acid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-Bromo-4-[(4-methylpiperazin-1-yl)methyl]benzoic acid

There total 4 articles about 3-Bromo-4-[(4-methylpiperazin-1-yl)methyl]benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 7697-26-9
3-bromo-4-methylbenzoic acid

: 765269-29-2
3-bromo-4-(4-methyl-piperazin-1-ylmethyl)-benzoic acid

Guidance literature:: Multi-step reaction with 4 steps

1: H₂SO₄ / Heating

2: N-bromosuccinimide / (PhCO)2O₂ / CCl₄ / Heating

3: K₂CO₃ / tetrahydrofuran / 20 °C

4: aq. NaOH / Heating

With sodium hydroxide; N-Bromosuccinimide; sulfuric acid; potassium carbonate; dibenzoyl peroxide; In tetrahydrofuran; tetrachloromethane;
DOI:10.1016/j.bmcl.2005.11.042

Reference yield:

: 147962-81-0
ethyl 3-bromo-4-methylbenzoate

: 765269-29-2
3-bromo-4-(4-methyl-piperazin-1-ylmethyl)-benzoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: N-bromosuccinimide / (PhCO)2O₂ / CCl₄ / Heating

2: K₂CO₃ / tetrahydrofuran / 20 °C

3: aq. NaOH / Heating

With sodium hydroxide; N-Bromosuccinimide; potassium carbonate; dibenzoyl peroxide; In tetrahydrofuran; tetrachloromethane;
DOI:10.1016/j.bmcl.2005.11.042

Reference yield:

: 113641-88-6
3-bromo-4-bromomethyl-benzoic acid ethyl ester

: 765269-29-2
3-bromo-4-(4-methyl-piperazin-1-ylmethyl)-benzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: K₂CO₃ / tetrahydrofuran / 20 °C

2: aq. NaOH / Heating

With sodium hydroxide; potassium carbonate; In tetrahydrofuran;
DOI:10.1016/j.bmcl.2005.11.042