3-(4-bromo-1H-pyrazol-1-yl)propanenitrile(SALTDATA: FREE)

Base Information

• Chemical Name: 3-(4-bromo-1H-pyrazol-1-yl)propanenitrile(SALTDATA: FREE)
• CAS No.: 1007518-24-2
• Molecular Formula: C₆H₆BrN₃
• Molecular Weight: 200.038
• Hs Code.: 2933199090
• Mol file: 1007518-24-2.mol

Synonyms:3-(4-bromo-1H-pyrazol-1-yl)propanenitrile(SALTDATA: FREE)

Chemical Property of 3-(4-bromo-1H-pyrazol-1-yl)propanenitrile(SALTDATA: FREE)

Chemical Property:

• PSA: 41.61000
• LogP: 1.55928

Purity/Quality:

97% ^*data from raw suppliers

3-(4-bromo-1H-pyrazol-1-yl)propanenitrile ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-(4-bromo-1H-pyrazol-1-yl)propanenitrile(SALTDATA: FREE)

There total 1 articles about 3-(4-bromo-1H-pyrazol-1-yl)propanenitrile(SALTDATA: FREE) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

4-bromo-1H-pyrazole (2075-45-8) + bromopropionitrile (2417-90-5) → 3-(4-bromo-1H-pyrazol-1-yl)propanenitrile (1007518-24-2)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 12h;

Reference yield: 36.0%

3-(4-bromo-1H-pyrazol-1-yl)propanenitrile (1007518-24-2) + bis(pinacol)diborane (73183-34-3) → 3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propanenitrile (1022092-33-6)

Guidance literature:

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; In 1,4-dioxane; at 115 ℃; Inert atmosphere;

Reference yield:

3-(4-bromo-1H-pyrazol-1-yl)propanenitrile (1007518-24-2) → N-(3-((7-(1-(2-cyanoethyl)-1H-pyrazol-4-yl)-5H-pyrrolo[2,3-b]pyrazin-2-yl)oxy)phenyl)acrylamide

Guidance literature:

Multi-step reaction with 3 steps

1.1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate / 1,4-dioxane / 115 °C / Inert atmosphere

2.1: sodium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,4-dioxane / 6 h / 70 °C / Inert atmosphere

3.1: trifluoroacetic acid / dichloromethane / 8 h / 20 °C

3.2: 20 °C / pH 8-9

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; sodium carbonate; trifluoroacetic acid; In 1,4-dioxane; dichloromethane;

upstream raw materials:

4-bromo-1H-pyrazole

bromopropionitrile

Downstream raw materials:

3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propanenitrile

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

✦Write with AI

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1007518-24-2 3-(4-bromo-1H-pyrazol-1-yl)propanenitrile(SALTDATA: FREE)

Send

Send

Metric Ton KG G Pound L ML

Send

Send