5-Chloro-2-hydroxy-2,4,6-cycloheptatrien-1-one

Base Information

• Chemical Name: 5-Chloro-2-hydroxy-2,4,6-cycloheptatrien-1-one
• CAS No.: 3084-17-1
• Molecular Formula: C7H5ClO2
• Molecular Weight: 156.569
• Mol file: 3084-17-1.mol

Synonyms:2-Hydroxy-5-chloro-2,4,6-cycloheptatriene-1-one;2-Hydroxy-5-chlorocyclohepta-2,4,6-trien-1-one;5-Chloro-2-hydroxy-2,4,6-cycloheptatrien-1-one;5-Chloro-2-hydroxy-2,4,6-cycloheptatriene-1-one

Chemical Property of 5-Chloro-2-hydroxy-2,4,6-cycloheptatrien-1-one

Chemical Property:

• PSA: 37.30000
• LogP: 1.40580

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-Chloro-2-hydroxy-2,4,6-cycloheptatrien-1-one

There total 9 articles about 5-Chloro-2-hydroxy-2,4,6-cycloheptatrien-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

4-chloro-2-hydroxymethylphenol (5330-38-1) → 5-chloro-5-tropolone (3084-17-1)

Guidance literature:

4-chloro-2-hydroxymethylphenol; With sodium periodate; In methanol; water; at 4 ℃; for 0.0833333h;

With sodium dithionite; In methanol; water; at 4 ℃; for 0.0333333h; Further stages;

DOI:10.1002/cbic.200900631

Reference yield:

5-aminotropolone (7021-46-7) → 5-chloro-5-tropolone (3084-17-1)

Guidance literature:

With hydrogenchloride; copper(l) chloride; sodium nitrite; In water; at 50 ℃; for 12h;

Reference yield:

→ 5-chloro-5-tropolone (3084-17-1)

Guidance literature:

With copper dichloride;

DOI:10.1021/ja01148a559

upstream raw materials:

2,5-dihydroxycyclohepta-2,4,6-trien-1-one

(1S,3S,4R,6R)-7,7-Dichloro-bicyclo[4.1.0]heptane-3,4-diol

2-hydroxy-2,4,6-cycloheptatrien-1-one

4-chloro-2-hydroxymethylphenol

Downstream raw materials:

2,5-dichloro-benzaldehyde

3,4-dichlorobenzaldehyde