Technology Process of [2-(Propan-2-yl)cyclopropyl]benzene
There total 6 articles about [2-(Propan-2-yl)cyclopropyl]benzene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
methanesulfonyl chloride; 2-(trans-2-Phenylcyclopropyl)1-propanol;
With
triethylamine;
In
tetrahydrofuran;
at -30 ℃;
With
lithium triethylborohydride;
In
tetrahydrofuran;
at -78 ℃;
DOI:10.1021/tx9800295
- Guidance literature:
-
With
hydrazine hydrate;
Erhitzen des entstandenen, nicht naeher beschriebenen (+-)-3-Isopropyl-5-phenyl-Δ2-pyrazolins mit KOH in Gegenwart von Platin-Asbest;
DOI:10.1021/ja01231a057
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: 94 percent / CH2Cl2; diethyl ether
2.1: 42 percent / Lithium bis(trimethylsilyl)amid
3.1: 72 percent / LiAlH4 / tetrahydrofuran / 2 h / 0 °C
4.1: Et3N / tetrahydrofuran / -30 °C
4.2: LiEt3BH / tetrahydrofuran / -78 °C
With
lithium aluminium tetrahydride; triethylamine; lithium hexamethyldisilazane;
In
tetrahydrofuran; diethyl ether; dichloromethane;
1.1: Esterification / 2.1: Metallation / 2.2: Methylation / 3.1: Reduction / 4.1: Substitution / 4.2: Reduction;
DOI:10.1021/tx9800295
