N-(tert-butoxycarbonyl)-3-imidazol-1-yl-L-alanine

Base Information

Chemical Name:N-(tert-butoxycarbonyl)-3-imidazol-1-yl-L-alanine
CAS No.:122225-53-0
Molecular Formula:C₁₁H₁₇N₃O₄
Molecular Weight:255.274
Hs Code.:
DSSTox Substance ID:DTXSID90434234
Wikidata:Q82248583
Mol file:122225-53-0.mol

Synonyms:122225-53-0;Boc-beta-imidazolyl-L-Ala;(2S)-3-imidazol-1-yl-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic Acid;(S)-2-((tert-Butoxycarbonyl)amino)-3-(1H-imidazol-1-yl)propanoic acid;(S)-2-(tert-butoxycarbonylamino)-3-(1H-imidazol-1-yl)propanoic acid;(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-(1H-imidazol-1-yl)propanoic acid;1260641-67-5;N-(tert-butoxycarbonyl)-3-imidazol-1-yl-L-alanine;Boc-(S)-2-amino-3-(imidazol-1-yl)propanoic acid;SCHEMBL13392169;DTXSID90434234;N-(tert-Butoxycarbonyl)-3-(1H-imidazol-1-yl)-L-alanine

Suppliers and Price of N-(tert-butoxycarbonyl)-3-imidazol-1-yl-L-alanine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 16 raw suppliers

Chemical Property of N-(tert-butoxycarbonyl)-3-imidazol-1-yl-L-alanine

Chemical Property:

XLogP3:0.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:255.12190603
Heavy Atom Count:18
Complexity:314

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC(CN1C=CN=C1)C(=O)O
Isomeric SMILES:CC(C)(C)OC(=O)N[C@@H](CN1C=CN=C1)C(=O)O

Technology Process of N-(tert-butoxycarbonyl)-3-imidazol-1-yl-L-alanine

There total 2 articles about N-(tert-butoxycarbonyl)-3-imidazol-1-yl-L-alanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 288-32-4
1H-imidazole

: 98541-64-1
(S)-3-(tert-butoxycarbonylamino)-oxetan-2-one

: 122225-53-0,760170-43-2
N-(tert-butoxycarbonyl)-3-imidazol-1-yl-L-alanine

Guidance literature:: In acetonitrile; at 20 ℃; for 28.08h; Inert atmosphere;

Reference yield: 55.0%

: 98541-64-1
(S)-3-(tert-butoxycarbonylamino)-oxetan-2-one

: 18156-74-6
1-(Trimethylsilyl)imidazole

: 122225-53-0,760170-43-2
N-(tert-butoxycarbonyl)-3-imidazol-1-yl-L-alanine

Guidance literature:: In acetonitrile; at 20 ℃;
DOI:10.1016/j.bmcl.2007.05.043

Reference yield: 47.0%

: 122621-77-6
(2S,3R,4S)-2-amino-1-cyclohexyl-3,4-dihydroxy-6-methylheptane

: 122225-53-0,760170-43-2
N-(tert-butoxycarbonyl)-3-imidazol-1-yl-L-alanine

: 136010-45-2
N-(tert-butoxycarbonyl)-3-imidazol-1-yl-L-alanine amide of (2S,3R,4S)-2-amino-1-cyclohexyl-3,4-dihydroxy-6-methylheptane

Guidance literature:: With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; 1.) -23 deg C, 2 h, 2.) RT, 15 h;
DOI:10.1021/jm00056a005