5-(5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl)nicotinamide

Base Information

Chemical Name:5-(5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl)nicotinamide
CAS No.:1272353-80-6
Molecular Formula:C₂₆H₂₀N₆O
Molecular Weight:432.484
Hs Code.:
Mol file:1272353-80-6.mol

Synonyms:5-(5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl)nicotinamide

Suppliers and Price of 5-(5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl)nicotinamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 5-(5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl)nicotinamide

Chemical Property:

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

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Technology Process of 5-(5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl)nicotinamide

There total 2 articles about 5-(5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl)nicotinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 24.0%

: 1272354-22-9
5-(5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl)nicotinonitrile

: 1272353-80-6
5-(5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl)nicotinamide

Guidance literature:: With dihydrogen peroxide; sodium hydroxide; In tetrahydrofuran; water; at 0 - 20 ℃; for 16h; Inert atmosphere;
DOI:10.1021/acs.jmedchem.6b01889

Reference yield:

: 402718-29-0
3-cyanopyridine-5-boronic acid pinacol ester

: 1272353-93-1
2-chloro-5-phenyl-N-(pyridin-2-ylmethyl)quinazolin-4-amine

: 1272353-80-6
5-(5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl)nicotinamide

Guidance literature:: Multi-step reaction with 2 steps

1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate / N,N-dimethyl-formamide / 2 h / 110 °C / Inert atmosphere

2: sodium hydroxide; dihydrogen peroxide / tetrahydrofuran; water / 16 h / 0 - 20 °C / Inert atmosphere

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; dihydrogen peroxide; potassium carbonate; sodium hydroxide; In tetrahydrofuran; water; N,N-dimethyl-formamide;
DOI:10.1021/acs.jmedchem.6b01889