1,3-Dimethyl-4-triphenylphosphoranylideneamino-pyrimdine-2,4-dione

Base Information

• Chemical Name: 1,3-Dimethyl-4-triphenylphosphoranylideneamino-pyrimdine-2,4-dione
• CAS No.: 99747-54-3
• Molecular Formula: C24H23N3O2P
• Molecular Weight: 415.431
• Mol file: 99747-54-3.mol

Synonyms:1,3-Dimethyl-4-triphenylphosphoranylideneamino-pyrimdine-2,4-dione

Chemical Property of 1,3-Dimethyl-4-triphenylphosphoranylideneamino-pyrimdine-2,4-dione

Chemical Property:

• PSA: 66.17000
• LogP: 2.89320

Purity/Quality:

95% ^*data from raw suppliers

1,3-DIMETHYL-4-TRIPHENYLPHOSPHORANYLIDENEAMINO-PYRIMIDINE-2,4-DIONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,3-Dimethyl-4-triphenylphosphoranylideneamino-pyrimdine-2,4-dione

There total 3 articles about 1,3-Dimethyl-4-triphenylphosphoranylideneamino-pyrimdine-2,4-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

6-azido-1,3-dimethylpyrimidine-2,4(1H,3H)-dione (61541-41-1) + triphenylphosphine (603-35-0) → 1,3-dimethyl-2,4-dioxo-6-<(triphenylphosphoranylidene)amino>-1,2,3,4-tetrahydropyrimidine (99747-54-3)

Guidance literature:

In toluene; for 0.5h; Heating;

DOI:10.1007/BF00807031

Reference yield: 63.0%

6-Amino-1,3-dimethylbarbituric acid (6642-31-5) + dichlorotriphenylphosphorane (2526-64-9) → 1,3-dimethyl-2,4-dioxo-6-<(triphenylphosphoranylidene)amino>-1,2,3,4-tetrahydropyrimidine (99747-54-3)

Guidance literature:

With hexachloroethane; triethylamine; In acetonitrile; at 25 ℃; for 16h;

DOI:10.1021/jo00352a005

Reference yield: 52.0%

6-azido-1,3-dimethylpyrimidine-2,4(1H,3H)-dione (61541-41-1) + allyltriphenylphosphonium bromide (1560-54-9) → 1,3-dimethyl-2,4-dioxo-6-<(triphenylphosphoranylidene)amino>-1,2,3,4-tetrahydropyrimidine (99747-54-3) + 1,3-dimethylpyrrolo<3,2-d>pyrimidine-2,4-dione (46155-89-9)

Guidance literature:

allyltriphenylphosphonium bromide; With lithium hydride; In butanone; at 20 ℃;

6-azido-1,3-dimethylpyrimidine-2,4(1H,3H)-dione; for 2h; Heating;

DOI:10.1002/hc.10048

upstream raw materials:

6-Amino-1,3-dimethylbarbituric acid

dichlorotriphenylphosphorane

6-azido-1,3-dimethylpyrimidine-2,4(1H,3H)-dione

triphenylphosphine

Downstream raw materials:

2,4,10-Trimethyl-6-(phenylimino)pyrido<1',2':3,4>pyrimido<4,5-d>pyrimidine-1,3(2H,4H)-dione

1,3-dimethyl-5-(2-nitroethenyl)-2,4-dioxo-6-<(triphenylphosphoranylidene)amino>-1,2,3,4-tetrahydropyrimidine

6-<(4-Nitrophenyl)imino>-2,4-dimethylpyrido<1',2':3,4>pyrimido<4,5-d>pyrimidine-1,3(2H,4H)-dione

6-<(4-Chlorophenyl)imino>-2,4-dimethylpyrido<1',2':3,4>pyrimido<4,5-d>pyrimidine-1,3(2H,4H)-dione