2-Amino-3-methylpentan-1-ol

Base Information

• Chemical Name: 2-Amino-3-methylpentan-1-ol
• CAS No.: 4379-13-9
• Molecular Formula: C6H15NO
• Molecular Weight: 117.191
• Hs Code.: 2922199090
• European Community (EC) Number: 246-371-4
• NSC Number: 64340
• DSSTox Substance ID: DTXSID20947529
• Nikkaji Number: J3.022.984C
• Mol file: 4379-13-9.mol

Synonyms:isoleucinol

Chemical Property of 2-Amino-3-methylpentan-1-ol

Chemical Property:

• Boiling Point: 196.9°Cat760mmHg
• PKA: 12.88±0.10(Predicted)
• Flash Point: 100.6°C
• PSA: 46.25000
• Density: 0.904g/cm³
• LogP: 1.85440
• Storage Temp.: −20°C
• XLogP3: 0.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 117.115364102
• Heavy Atom Count: 8
• Complexity: 56.5

Purity/Quality:

98% ^*data from raw suppliers

2-AMINO-3-METHYLPENTAN-1-OL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC(C)C(CO)N

Technology Process of 2-Amino-3-methylpentan-1-ol

There total 2 articles about 2-Amino-3-methylpentan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

DL-isoleucine (73-32-5,319-78-8,443-79-8,1509-34-8,1509-35-9,3107-04-8,7004-09-3,959215-79-3,18875-42-8) → (+/-)-erythro-2-amino-3-methyl-pentan-1-ol (4379-13-9,24629-25-2,88996-94-5,113349-34-1)

Guidance literature:

With tetrahydrofuran; lithium aluminium tetrahydride;

DOI:10.1007/BF00904133

Reference yield:

L-isoleucine (73-32-5,959215-79-3,18875-42-8) → (S)-(-)-2-amino-3-methylpentan-1-ol (4379-13-9,24629-25-2,88996-94-5,113349-34-1)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; Heating;

Reference yield: 91.0%

(S)-2-amino-3-methylpentanol (4379-13-9) + rac-1-(4-methoxyphenyl)-ethanol (3319-15-1) → 2-(1-methylpropyl)-5-(4-methoxyphenyl)-1H-pyrrole

Guidance literature:

With C₁₇H₁₁Cl₂N₃O₃Ru; potassium tert-butylate; In toluene; at 110 ℃;

DOI:10.1021/acs.organomet.8b00359

upstream raw materials:

DL-isoleucine

L-isoleucine

Downstream raw materials:

4-chloro-N-[(1S,2S)-1-(hydroxymethyl)-2-methylbutyl]-benzenesulfonamide

4-Iodo-N-[(1S,2S)-1-(hydroxymethyl)-2-methylbutyl]benzenesulfonamide

3-Nitro-4-chloro-N-[(1S,2 S)-1-(hydroxymethyl)-2-methylbutyl]benzenesulfonamide

2-(1-methylpropyl)-5-phenyl-1H-pyrrole