methyl 2-bromo-[1,2,4]triazolo[1,5-a]pyridine-7-carboxylate

Base Information

Chemical Name:methyl 2-bromo-[1,2,4]triazolo[1,5-a]pyridine-7-carboxylate
CAS No.:1622993-11-6
Molecular Formula:
Molecular Weight:0
Hs Code.:

Synonyms:methyl 2-bromo-[1,2,4]triazolo[1,5-a]pyridine-7-carboxylate;2-Bromo-[1,2,4]triazolo[1,5-a]pyridine-7-carboxylic acid methyl ester

Suppliers and Price of methyl 2-bromo-[1,2,4]triazolo[1,5-a]pyridine-7-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 9 raw suppliers

Chemical Property of methyl 2-bromo-[1,2,4]triazolo[1,5-a]pyridine-7-carboxylate

Chemical Property:

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of methyl 2-bromo-[1,2,4]triazolo[1,5-a]pyridine-7-carboxylate

There total 2 articles about methyl 2-bromo-[1,2,4]triazolo[1,5-a]pyridine-7-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1094107-42-2
methyl 2-amino[1,2,4]triazolo[1,5-a]pyridin-7-carboxylate

: 1622993-11-6
methyl 2-bromo-[1,2,4]triazolo[1,5-a]pyridin-7-carboxylate

Guidance literature:: With copper(I) bromide; In acetonitrile; at 70 - 75 ℃; for 1h;

Reference yield:

: 6937-03-7
methyl 2-aminoisonicotinate

: 1622993-11-6
methyl 2-bromo-[1,2,4]triazolo[1,5-a]pyridin-7-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: hydroxylamine hydrochloride; N-ethyl-N,N-diisopropylamine / 1,4-dioxane; methanol; ethanol / 15 h / 60 °C

2: copper(I) bromide / acetonitrile / 1 h / 70 - 75 °C

With hydroxylamine hydrochloride; N-ethyl-N,N-diisopropylamine; copper(I) bromide; In 1,4-dioxane; methanol; ethanol; acetonitrile;

Reference yield:

: 1622993-11-6
methyl 2-bromo-[1,2,4]triazolo[1,5-a]pyridin-7-carboxylate

: 4-(4-(difluoromethyl)thiazol-2-yl)-1-methyl-N-(2-phenyl[1,2,4]triazolo[1,5-a]pyridin-7-yl)-1H-pyrazol-5-carboxamide

Guidance literature:: Multi-step reaction with 5 steps

1: water; sodium hydroxide / methanol / 0.5 h

2: diphenyl phosphoryl azide; triethylamine / 3 h / 20 - 100 °C / Molecular sieve

3: hydrogenchloride / 1,4-dioxane / 0.07 h / Reflux

4: 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; N-ethyl-N,N-diisopropylamine / tetrahydrofuran; ethyl acetate / 12 h / 100 °C

5: tetrakis(triphenylphosphine) palladium⁽⁰⁾; caesium carbonate / water; 1,2-dimethoxyethane / 3 h / 100 °C

With hydrogenchloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; diphenyl phosphoryl azide; water; caesium carbonate; 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; triethylamine; N-ethyl-N,N-diisopropylamine; sodium hydroxide; In tetrahydrofuran; 1,4-dioxane; methanol; 1,2-dimethoxyethane; water; ethyl acetate;