[3-Methoxy-5-(trifluoroMethyl)phenyl]Methanol

Base Information

• Chemical Name: [3-Methoxy-5-(trifluoroMethyl)phenyl]Methanol
• CAS No.: 916420-98-9
• Molecular Formula: C9H9F3O2
• Molecular Weight: 206.164
• Hs Code.: 2909499000
• Mol file: 916420-98-9.mol

Synonyms:[3-Methoxy-5-(trifluoroMethyl)phenyl]Methanol;[3-Methoxy-5-(trifluoromethyl)phenyl]methanol, 3-(Hydroxymethyl)-5-methoxybenzotrifluoride;3-Methoxy-5-(trifluoromethyl)benzyl alcohol 97%;3-Methoxy-5-(trifluoromethyl)benzylalcohol97%

Chemical Property of [3-Methoxy-5-(trifluoroMethyl)phenyl]Methanol

Chemical Property:

• PSA: 29.46000
• LogP: 2.20630

Purity/Quality:

98% ^*data from raw suppliers

3-Methoxy-5-(trifluoromethyl)benzyl alcohol 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of [3-Methoxy-5-(trifluoroMethyl)phenyl]Methanol

There total 3 articles about [3-Methoxy-5-(trifluoroMethyl)phenyl]Methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

3-methoxy-5-trifluoromethyl-benzoic acid methyl ester (1003843-90-0) → [3-methoxy-5-(trifluoromethyl)phenyl]methanol (916420-98-9)

Guidance literature:

3-methoxy-5-trifluoromethyl-benzoic acid methyl ester; With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 20 ℃; for 2h;

With sodium sulfate; In tetrahydrofuran; diethyl ether;

Reference yield:

3-methoxy-5-(trifluoromethyl)benzoic acid (53985-48-1) → [3-methoxy-5-(trifluoromethyl)phenyl]methanol (916420-98-9)

Guidance literature:

3-methoxy-5-(trifluoromethyl)benzoic acid; With lithium aluminium tetrahydride; In tetrahydrofuran; at 5 - 20 ℃; for 2h;

With sodium hydroxide; In tetrahydrofuran; water;

Reference yield:

→ [3-methoxy-5-(trifluoromethyl)phenyl]methanol (916420-98-9)

Guidance literature:

upstream raw materials:

3-methoxy-5-trifluoromethyl-benzoic acid methyl ester

3-methoxy-5-(trifluoromethyl)benzoic acid

Downstream raw materials:

3-methoxy-5-(trifluoromethyl)benzyl bromide

[3-methoxy-5-(trifluoromethyl)phenyl]acetonitrile

Refernces

• 1、 -. "AMINO-PIPERIDINE DERIVATIVES AS CETP INHIBITORS". Page/Page column 161. . Retrieved 2008/06/13.
• 2、 -. "NOVEL COMPOUNDS". Page/Page column 46. . Retrieved 2008/06/13.