1-(Bromomethyl)-3-methoxy-5-(trifluoromethyl)benzene, 3-(Bromomethyl)-5-(trifluoromethyl)phenyl methyl ether

Base Information

• Chemical Name: 1-(Bromomethyl)-3-methoxy-5-(trifluoromethyl)benzene, 3-(Bromomethyl)-5-(trifluoromethyl)phenyl methyl ether
• CAS No.: 916421-00-6
• Molecular Formula: C9H8BrF3O
• Molecular Weight: 269.061
• Hs Code.: 2909309090
• Mol file: 916421-00-6.mol

Synonyms:1-(Bromomethyl)-3-methoxy-5-(trifluoromethyl)benzene, 3-(Bromomethyl)-5-(trifluoromethyl)phenyl methyl ether;3-Methoxy-5-(trifluoromethyl)benzyl bromide 97%;3-Methoxy-5-(trifluoromethyl)benzylbromide97%

Chemical Property of 1-(Bromomethyl)-3-methoxy-5-(trifluoromethyl)benzene, 3-(Bromomethyl)-5-(trifluoromethyl)phenyl methyl ether

Chemical Property:

• Boiling Point: 241.3±40.0 °C(Predicted)
• PSA: 9.23000
• Density: 1.524±0.06 g/cm3(Predicted)
• LogP: 3.60890
• Storage Temp.: 2-8°C

Purity/Quality:

98% ^*data from raw suppliers

3-Methoxy-5-(trifluoromethyl)benzyl bromide 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(Bromomethyl)-3-methoxy-5-(trifluoromethyl)benzene, 3-(Bromomethyl)-5-(trifluoromethyl)phenyl methyl ether

There total 2 articles about 1-(Bromomethyl)-3-methoxy-5-(trifluoromethyl)benzene, 3-(Bromomethyl)-5-(trifluoromethyl)phenyl methyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

[3-methoxy-5-(trifluoromethyl)phenyl]methanol (916420-98-9) → 3-methoxy-5-(trifluoromethyl)benzyl bromide (916421-00-6)

Guidance literature:

With N-Bromosuccinimide; triphenylphosphine; In dichloromethane; at 0 - 20 ℃; for 1h;

Reference yield:

→ 3-methoxy-5-(trifluoromethyl)benzyl bromide (916421-00-6)

Guidance literature:

Reference yield: 51.0%

3-methoxy-5-(trifluoromethyl)benzyl bromide (916421-00-6) + 4-(1H-pyrazol-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine → 1-(3-methoxy-5-(trifluoromethyl)benzyl)-4-(1H-pyrazol-1-yl)-1H-pyrazolo[3,4-d]pyrimidine-6-amine

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 40 ℃; for 8h;

upstream raw materials:

[3-methoxy-5-(trifluoromethyl)phenyl]methanol