4-Allyl-3-oxooctanoic acid methyl ester

Base Information

• Chemical Name: 4-Allyl-3-oxooctanoic acid methyl ester
• CAS No.: 30414-60-9
• Molecular Formula: C₁₂H₂₀O₃
• Molecular Weight: 212.289
• Hs Code.: 2918300090
• Mol file: 30414-60-9.mol

Synonyms:3-Oxo-4-(2-propenyl)octanoic acid methyl ester;4-Allyl-3-oxooctanoic acid methyl ester

Chemical Property of 4-Allyl-3-oxooctanoic acid methyl ester

Chemical Property:

• PSA: 43.37000
• LogP: 2.50110

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Allyl-3-oxooctanoic acid methyl ester

There total 3 articles about 4-Allyl-3-oxooctanoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

acetoacetic acid methyl ester (105-45-3) → Methyl 3-Oxo-4-allyloctanoate (30414-60-9)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) NaH, THF, (ii) nBuLi, hexane, (iii) /BRN= 1098260/, aq. HCl, Et₂O

2: (i) NaH, (ii) nBuLi, THF, (iii) /BRN= 605308/, aq. HCl, Et₂O

DOI:10.1021/ja00811a023

Reference yield:

methyl 3-oxooctanoate (22348-95-4) + allyl bromide (106-95-6) → Methyl 3-Oxo-4-allyloctanoate (30414-60-9)

Guidance literature:

Multistep reaction; (i) NaH, (ii) nBuLi, THF, (iii) /BRN= 605308/, aq. HCl, Et₂O;

DOI:10.1021/ja00811a023

Reference yield:

→ Methyl 3-Oxo-4-allyloctanoate (30414-60-9)

Guidance literature:

CH3-(CH2)4-CO-CH2-CO2CH3, Allylbromid;

DOI:10.1021/ja00725a088

upstream raw materials:

methyl 3-oxooctanoate

allyl bromide

acetoacetic acid methyl ester