Technology Process of (S)-2-Ethylpiperidine hydrochloride
There total 7 articles about (S)-2-Ethylpiperidine hydrochloride which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
(R)-1-((R)-1-phenylethyl)-2-vinylpiperidine;
With
hydrogen;
In
methanol;
at 20 ℃;
for 15h;
under 1900.13 Torr;
With
hydrogenchloride;
In
water;
at 20 ℃;
for 1h;
DOI:10.24820/ark.5550190.p010.591
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: tris-(dibenzylideneacetone)dipalladium(0); 1,4-di(diphenylphosphino)-butane / tetrahydrofuran / 24 h / 20 °C / Schlenk technique; Inert atmosphere
2.1: ; hydrogen / methanol / 15 h / 20 °C / 1900.13 Torr
2.2: 1 h / 20 °C
With
tris-(dibenzylideneacetone)dipalladium(0); hydrogen; 1,4-di(diphenylphosphino)-butane;
In
tetrahydrofuran; methanol;
DOI:10.24820/ark.5550190.p010.591
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: diisobutylaluminium hydride / dichloromethane / -78 °C
2.1: dichloromethane / 20 °C
3.1: diisobutylaluminium hydride / diethyl ether / 0 °C
4.1: pyridine / dichloromethane / 0 - 20 °C
5.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 20 °C
6.1: tris-(dibenzylideneacetone)dipalladium(0); 1,4-di(diphenylphosphino)-butane / tetrahydrofuran / 24 h / 20 °C / Schlenk technique; Inert atmosphere
7.1: ; hydrogen / methanol / 15 h / 20 °C / 1900.13 Torr
7.2: 1 h / 20 °C
With
pyridine; tris-(dibenzylideneacetone)dipalladium(0); hydrogen; diisobutylaluminium hydride; N-ethyl-N,N-diisopropylamine; 1,4-di(diphenylphosphino)-butane;
In
tetrahydrofuran; methanol; diethyl ether; dichloromethane; N,N-dimethyl-formamide;
2.1: |Wittig Olefination;
DOI:10.24820/ark.5550190.p010.591