4-((1-Methylpiperidin-4-yl)oxy)aniline

Base Information

Chemical Name:4-((1-Methylpiperidin-4-yl)oxy)aniline
CAS No.:358789-72-7
Molecular Formula:C12H18N2O
Molecular Weight:206.288
Hs Code.:2933399090
European Community (EC) Number:844-332-1
DSSTox Substance ID:DTXSID70587934
Wikidata:Q82480406
Mol file:358789-72-7.mol

Synonyms:358789-72-7;4-((1-Methylpiperidin-4-yl)oxy)aniline;4-[(1-methylpiperidin-4-yl)oxy]aniline;4-(1-methylpiperidin-4-yl)oxyaniline;(4-[(1-METHYLPIPERIDIN-4-YL)OXY]PHENYL)AMINE;4-(1-Methyl-piperidin-4-yloxy)-phenylamine;4-[(1-Methyl-4-piperidinyl)oxy]aniline;Benzenamine, 4-[(1-methyl-4-piperidinyl)oxy]-;SCHEMBL188685;DTXSID70587934;MFCD04970985;STK691688;AKOS000311166;MCULE-7298320590;SB36812;AS-66151;DA-18389;CS-0136606;N12636;EN300-6317421;4-[(1-Methylpiperidin-4-yl)oxy]aniline, AldrichCPR

Suppliers and Price of 4-((1-Methylpiperidin-4-yl)oxy)aniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-((1-Methylpiperidin-4-yl)oxy)aniline
250mg
$ 60.00

Sigma-Aldrich
4-[(1-Methylpiperidin-4-yl)oxy]aniline Aldrich
1g
$ 245.00

Matrix Scientific
4-[(1-Methyl-4-piperidinyl)oxy]aniline
10g
$ 1872.00

Matrix Scientific
4-[(1-Methyl-4-piperidinyl)oxy]aniline
5g
$ 1296.00

Matrix Scientific
4-[(1-Methyl-4-piperidinyl)oxy]aniline
1g
$ 540.00

J&W Pharmlab
4-(1-Methyl-piperidin-4-yloxy)-phenylamine 96%
500mg
$ 349.00

J&W Pharmlab
4-(1-Methyl-piperidin-4-yloxy)-phenylamine 96%
1g
$ 598.00

J&W Pharmlab
4-(1-Methyl-piperidin-4-yloxy)-phenylamine 96%
5g
$ 1998.00

Crysdot
4-((1-Methylpiperidin-4-yl)oxy)aniline 95+%
25g
$ 990.00

Crysdot
4-((1-Methylpiperidin-4-yl)oxy)aniline 95+%
10g
$ 644.00

Total 9 raw suppliers

Chemical Property of 4-((1-Methylpiperidin-4-yl)oxy)aniline

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:74-76 °C
Boiling Point:337.62°C at 760 mmHg
PKA:8.52±0.10(Predicted)
Flash Point:157.987°C
PSA：38.49000
Density:1.09g/cm³
LogP:2.26090
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:206.141913202
Heavy Atom Count:15
Complexity:182

Purity/Quality:

99%, ^*data from raw suppliers

4-((1-Methylpiperidin-4-yl)oxy)aniline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCC(CC1)OC2=CC=C(C=C2)N
Uses 4-((1-Methylpiperidin-4-yl)oxy)aniline is used in preparation of Phenylacetamides as inhibitors of ROCK.

Technology Process of 4-((1-Methylpiperidin-4-yl)oxy)aniline

There total 5 articles about 4-((1-Methylpiperidin-4-yl)oxy)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 358789-72-7
4-(1-methylpiperidin-4-yloxy)benzenamine

Guidance literature:

Reference yield:

: 791577-47-4
4-(1-Methylpiperidin-4-yloxy)nitrobenzene

: 358789-72-7
4-(1-methylpiperidin-4-yloxy)benzenamine

Guidance literature:: With ethanol; nickel; at 20 ℃; under 3677.5 Torr; Hydrogenation;
DOI:10.1039/jr9540001795

Reference yield:

: 106-52-5
N-methyl-4-hydroxypiperidine

: 358789-72-7
4-(1-methylpiperidin-4-yloxy)benzenamine

Guidance literature:: Multi-step reaction with 2 steps

1: potassium; tert-butyl alcohol / Behandeln des Reaktionsgemisches mit 1-Fluor-4-nitro-benzol

2: Raney nickel; ethanol / 20 °C / 3677.5 Torr / Hydrogenation

With ethanol; potassium; nickel; tert-butyl alcohol;
DOI:10.1039/jr9540001795