2-(5-chloro-2-((3-(4-methylpiperazin-1-yl)propyl)amino)pyrimidin-4-yl)-N-cyclopropylbenzo[b]thiophene-4-carboxamide

Base Information

Chemical Name:2-(5-chloro-2-((3-(4-methylpiperazin-1-yl)propyl)amino)pyrimidin-4-yl)-N-cyclopropylbenzo[b]thiophene-4-carboxamide
CAS No.:946518-61-2
Molecular Formula:C₂₄H₂₉ClN₆OS
Molecular Weight:485.053
Hs Code.:
DSSTox Substance ID:DTXSID001106528
Mol file:946518-61-2.mol

Synonyms:LY2409881

Suppliers and Price of 2-(5-chloro-2-((3-(4-methylpiperazin-1-yl)propyl)amino)pyrimidin-4-yl)-N-cyclopropylbenzo[b]thiophene-4-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
LY2409881 98+%
100mg
$ 565.00

Crysdot
LY2409881 98+%
10mg
$ 136.00

ChemScene
LY2409881
10mg
$ 216.00

ChemScene
LY2409881
100mg
$ 1092.00

ChemScene
LY2409881
50mg
$ 780.00

ChemScene
LY2409881
5mg
$ 132.00

Chemenu
2-(5-chloro-2-((3-(4-methylpiperazin-1-yl)propyl)amino)pyrimidin-4-yl)-N-cyclopropylbenzo[b]thiophene-4-carboxamide 98%
100mg
$ 534.00

Total 6 raw suppliers

Chemical Property of 2-(5-chloro-2-((3-(4-methylpiperazin-1-yl)propyl)amino)pyrimidin-4-yl)-N-cyclopropylbenzo[b]thiophene-4-carboxamide

Chemical Property:

PSA：101.63000
LogP:4.29300
XLogP3:3.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:8
Exact Mass:484.1812084
Heavy Atom Count:33
Complexity:661

Purity/Quality:

97% ^*data from raw suppliers

LY2409881 98+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCN(CC1)CCCNC2=NC=C(C(=N2)C3=CC4=C(C=CC=C4S3)C(=O)NC5CC5)Cl

Technology Process of 2-(5-chloro-2-((3-(4-methylpiperazin-1-yl)propyl)amino)pyrimidin-4-yl)-N-cyclopropylbenzo[b]thiophene-4-carboxamide

There total 1 articles about 2-(5-chloro-2-((3-(4-methylpiperazin-1-yl)propyl)amino)pyrimidin-4-yl)-N-cyclopropylbenzo[b]thiophene-4-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 4572-03-6
3-(N-methylpiperazino)propylamine

: 946518-07-6
2-(2,5-dichloropyrimidin-4-yl)-benzo[b]thiophene-4-carboxylic acid cyclopropylamide

: 946518-61-2
LY2409881

Guidance literature:: 3-(N-methylpiperazino)propylamine; 2-(2,5-dichloropyrimidin-4-yl)-benzo[b]thiophene-4-carboxylic acid cyclopropylamide; In 1,4-dioxane; at 20 - 95 ℃; for 6h;

With methanol; lithium hydroxide; water; In dichloromethane;