2-CHLORO-5-PICOLINOYLPYRIDINE

Base Information

• Chemical Name: 2-CHLORO-5-PICOLINOYLPYRIDINE
• CAS No.: 884504-81-8
• Molecular Formula: C₁₁H₇ClN₂O
• Molecular Weight: 218.642
• Hs Code.: 2933399090
• Mol file: 884504-81-8.mol

Synonyms:2-CHLORO-5-PICOLINOYLPYRIDINE;(6-chloropyridin-3-yl)(pyridin-2-yl)methanone

Chemical Property of 2-CHLORO-5-PICOLINOYLPYRIDINE

Chemical Property:

• Vapor Pressure: 3.77E-06mmHg at 25°C
• Boiling Point: 385.6°C at 760 mmHg
• Flash Point: 187°C
• PSA: 42.85000
• Density: 1.317g/cm³
• LogP: 2.36100

Purity/Quality:

97% ^*data from raw suppliers

2-chloro-5-picolinoylpyridine 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-CHLORO-5-PICOLINOYLPYRIDINE

There total 1 articles about 2-CHLORO-5-PICOLINOYLPYRIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

6-Chloronicotinoyl chloride (58757-38-3) + pyridin-2-ylzinc(II) bromide → C11H7ClN2O (884504-81-8)

Guidance literature:

In tetrahydrofuran; at 20 ℃; for 3h; Inert atmosphere;

DOI:10.1016/j.tetlet.2009.07.004

upstream raw materials:

6-Chloronicotinoyl chloride

Refernces

• 1、 Kim, Seung-Hoi,Rieke, Reuben D.. "A facile synthetic route for 2-pyridyl derivatives: direct preparation of a stable 2-pyridylzinc bromide and its copper-free and pd-catalyzed coupling reactions". supporting information; experimental part. p. 5329 - 5331. Retrieved 2009/12/06.