1-Pyrrolidinecarboxylic acid, 2,2'-([1,1'-biphenyl]-4,4'-diyldi-1H-iMidazole-5,2-diyl)bis-, 1,1'-bis(1,1-diMethylethyl) ester, (2S,2'S)-

Base Information

Chemical Name:1-Pyrrolidinecarboxylic acid, 2,2'-([1,1'-biphenyl]-4,4'-diyldi-1H-iMidazole-5,2-diyl)bis-, 1,1'-bis(1,1-diMethylethyl) ester, (2S,2'S)-
CAS No.:1007882-23-6
Molecular Formula:C36H44N6O4
Molecular Weight:624.783
Hs Code.:
Mol file:1007882-23-6.mol

Synonyms:1-Pyrrolidinecarboxylic acid, 2,2'-([1,1'-biphenyl]-4,4'-diyldi-1H-iMidazole-5,2-diyl)bis-, 1,1'-bis(1,1-diMethylethyl) ester, (2S,2'S)-;(2S,2'S)-di-tert-butyl 2,2'-(4,4'-([1,1'-biphenyl]-4,4'-diyl)bis(1H-iMidazole-4,2-diyl))bis(pyrrolidine-1-carboxylate);(2S,2'S)-;di-tert-butyl (2S,2'S)-2,2'-(4,4'-biphenyldiylbis(1H-imidazole-5,2-diyl))di(1-pyrrolidinecarboxylate);Daclatasvir Intermediate-2;(2S,2'S)-2,2'-[(1,1'-biphenyl)-4,4'-diyldi-1H-imidazole-5,2-diyl]bis-1-pyrrolidinecarboxylic acid ,1,1'-bis(1,1-dimethylethyl) ester;Daclatasvir Intermediates Ⅱ;Dacaltasvir Intermediate 02

Suppliers and Price of 1-Pyrrolidinecarboxylic acid, 2,2'-([1,1'-biphenyl]-4,4'-diyldi-1H-iMidazole-5,2-diyl)bis-, 1,1'-bis(1,1-diMethylethyl) ester, (2S,2'S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

CSNpharm
HCV-IN-30
100mg
$ 45.00

Crysdot
BIs(2-methyl-2-propanyl)(2S,2'S)-2,2'-[4,4'-biphenyldiylbis(1H-imidazole-4,2-diyl)]di(1-pyrrolidinecarboxylate) 95+%
25g
$ 970.00

Crysdot
BIs(2-methyl-2-propanyl)(2S,2'S)-2,2'-[4,4'-biphenyldiylbis(1H-imidazole-4,2-diyl)]di(1-pyrrolidinecarboxylate) 95+%
10g
$ 495.00

Crysdot
BIs(2-methyl-2-propanyl)(2S,2'S)-2,2'-[4,4'-biphenyldiylbis(1H-imidazole-4,2-diyl)]di(1-pyrrolidinecarboxylate) 95+%
5g
$ 297.00

Chemenu
di-tert-butyl2,2''-([1,1''-biphenyl]-4,4''-diylbis(1H-imidazole-4,2-diyl))(2S,2''S)-bis(pyrrolidine-1-carboxylate) 95%
5g
$ 281.00

Chemenu
di-tert-butyl2,2''-([1,1''-biphenyl]-4,4''-diylbis(1H-imidazole-4,2-diyl))(2S,2''S)-bis(pyrrolidine-1-carboxylate) 95%
1g
$ 102.00

Chemenu
di-tert-butyl2,2''-([1,1''-biphenyl]-4,4''-diylbis(1H-imidazole-4,2-diyl))(2S,2''S)-bis(pyrrolidine-1-carboxylate) 95%
10g
$ 468.00

Chemenu
di-tert-butyl2,2''-([1,1''-biphenyl]-4,4''-diylbis(1H-imidazole-4,2-diyl))(2S,2''S)-bis(pyrrolidine-1-carboxylate) 95%
25g
$ 916.00

ApexBio Technology
methyl N-[(2S)-1-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2S)-2-(methoxycarbonylamino)-3-methylbutanoyl]pyrrolidin-2-yl]-1H-imidazol-5-yl]phenyl]phenyl]-1H-imidazol-2-yl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate
100mg
$ 610.00

ApexBio Technology
methyl N-[(2S)-1-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2S)-2-(methoxycarbonylamino)-3-methylbutanoyl]pyrrolidin-2-yl]-1H-imidazol-5-yl]phenyl]phenyl]-1H-imidazol-2-yl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate
10mM (in 1mL DMSO)
$ 100.00

Total 68 raw suppliers

Chemical Property of 1-Pyrrolidinecarboxylic acid, 2,2'-([1,1'-biphenyl]-4,4'-diyldi-1H-iMidazole-5,2-diyl)bis-, 1,1'-bis(1,1-diMethylethyl) ester, (2S,2'S)-

Chemical Property:

Boiling Point:890.2±65.0 °C(Predicted)
PKA:12.83±0.10(Predicted)
PSA：116.44000
Density:1.220±0.06 g/cm3(Predicted)
LogP:8.15360
Storage Temp.:2-8°C

Purity/Quality:

99%, ^*data from raw suppliers

HCV-IN-30 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses (2S,2''S)-2,2''-([1,1''-Biphenyl]-4,4''-diyldi-1H-imidazole-5,2-diyl)bis-1-pyrrolidinecarboxylic Acid 1,1''-Bis(1,1-dimethylethyl) Ester is an antiviral agent and Daclatasvir (D101500) intermediate. Daclatasvir inhibits the HCV protein NS5A and thus can be used as a drug candidate for the treatment of hepatitis C (HCV).

Technology Process of 1-Pyrrolidinecarboxylic acid, 2,2'-([1,1'-biphenyl]-4,4'-diyldi-1H-iMidazole-5,2-diyl)bis-, 1,1'-bis(1,1-diMethylethyl) ester, (2S,2'S)-

There total 12 articles about 1-Pyrrolidinecarboxylic acid, 2,2'-([1,1'-biphenyl]-4,4'-diyldi-1H-iMidazole-5,2-diyl)bis-, 1,1'-bis(1,1-diMethylethyl) ester, (2S,2'S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%