Boc-NH-PEG11-CH2CH2NH2

Base Information

• Chemical Name: Boc-NH-PEG11-CH2CH2NH2
• CAS No.: 1233234-77-9
• Molecular Formula: C29H60N2O13
• Molecular Weight: 644.801
• Mol file: 1233234-77-9.mol

Synonyms:Boc-NH-PEG11-CH2CH2NH2;37-Amino-5,8,11,14,17,20,23,26,29,32,35-undecaoxa-2-azaheptatriacontanoic acid 1,1-dimethylethyl ester

Chemical Property of Boc-NH-PEG11-CH2CH2NH2

Chemical Property:

• PSA: 165.88000
• LogP: 1.74360

Purity/Quality:

98% ^*data from raw suppliers

BocNH-PEG11-CH2CH2NH2 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Boc-NH-PEG11-CH2CH2NH2

There total 6 articles about Boc-NH-PEG11-CH2CH2NH2 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

C29H58N4O13 → 37-amino-5, 8,11,14,17,20,23,26,29,32,35-undecaoxa-2-azaheptatriacontanoic acid tert-butyl ester (1233234-77-9)

Guidance literature:

With triphenylphosphine; In tetrahydrofuran; diethyl ether; water; at 0 - 20 ℃; Inert atmosphere;

Reference yield: 100.0%

→ 37-amino-5, 8,11,14,17,20,23,26,29,32,35-undecaoxa-2-azaheptatriacontanoic acid tert-butyl ester (1233234-77-9)

Guidance literature:

With hydrogenchloride; triphenylphosphine; In diethyl ether; ethyl acetate; Inert atmosphere;

Reference yield:

toluene-4-sulfonic acid 2-[2-(2-{2-[2-(2-hydroxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethyl ester (42749-28-0) → 37-amino-5, 8,11,14,17,20,23,26,29,32,35-undecaoxa-2-azaheptatriacontanoic acid tert-butyl ester (1233234-77-9)

Guidance literature:

Multi-step reaction with 4 steps

1.1: sodium azide / N,N-dimethyl-formamide / 1 h / 110 °C / Inert atmosphere

2.1: hydrogen; 5%-palladium/activated carbon / ethanol / 4 h / 20 °C

2.2: 3 h / 20 °C

3.1: sodium hydride / tetrahydrofuran; mineral oil / 0 °C / Inert atmosphere

3.2: 0 - 20 °C / Inert atmosphere

4.1: triphenylphosphine / tetrahydrofuran; water; diethyl ether / 0 - 20 °C / Inert atmosphere

With sodium azide; 5%-palladium/activated carbon; hydrogen; sodium hydride; triphenylphosphine; In tetrahydrofuran; diethyl ether; ethanol; water; N,N-dimethyl-formamide; mineral oil;

upstream raw materials:

toluene-4-sulfonic acid 2-[2-(2-{2-[2-(2-hydroxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethyl ester

17-azido-3,6,9,12,15-pentaoxaheptadecan-1-ol

tert-butyl N-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamate

2[-2-(2-{2-[2-(2-azido-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethyl p-tosylate

Refernces

• 1、 -. "NOVEL BENZODIAZEPINE DERIVATIVES AND USES THEREOF". . . Retrieved 2019/12/24.