N-Boc-PEG6-alcohol

Base Information

Chemical Name:N-Boc-PEG6-alcohol
CAS No.:331242-61-6
Molecular Formula:C17H35NO8
Molecular Weight:381.467
Hs Code.:2924190090
Mol file:331242-61-6.mol

Synonyms:N-(tert-butoxycarbonyl)-17-amino-3,6,9,12,15-pentaoxaheptadecane-1-ol;t-butyl 17-hydroxyl-3,6,9,12,15-pentaoxaheptadecylcarbamate;tert-butyl 17-hydroxy-3,6,9,12,15-pentaoxaheptadec-1-ylcarbamate;17-t-butyloxycarbonylamino-3,6,9,12,15-pentaoxaheptadecanol;

Suppliers and Price of N-Boc-PEG6-alcohol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

purepeg
BocNH-PEG6-OH min.95%
250 mg
$ 92.00

Crysdot
tert-Butyl(17-hydroxy-3,6,9,12,15-pentaoxaheptadecyl)carbamate 97%
250mg
$ 280.00

Crysdot
tert-Butyl(17-hydroxy-3,6,9,12,15-pentaoxaheptadecyl)carbamate 97%
1g
$ 625.00

Chemenu
17-(Boc-amino)-3,6,9,12,15-pentaoxa-1-heptadecanol 95%
1g
$ 638.00

BroadPharm
N-Boc-PEG6-alcohol 98%
1 G
$ 400.00

Apolloscientific
N-Boc-PEG6-alcohol
500mg
$ 740.00

AK Scientific
N-Boc-PEG6-alcohol
250mg
$ 397.00

Activate Scientific
17-(Boc-amino)-3,6,9,12,15-pentaoxa-1-heptadecanol 95%
1 g
$ 532.00

Acrotein
BocNH-PEG6-OH 97%
0.25g
$ 174.16

Total 15 raw suppliers

Chemical Property of N-Boc-PEG6-alcohol

Chemical Property:

Boiling Point:487.1±45.0 °C(Predicted)
PKA:12.23±0.46(Predicted)
PSA：104.71000
Density:1.087±0.06 g/cm3(Predicted)
LogP:0.97730
Solubility.:Soluble in DMSO, DCM, DMF

Purity/Quality:

97% ^*data from raw suppliers

BocNH-PEG6-OH min.95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Description N-Boc-PEG6-alcohol is a PEG linker containing a Boc protected amine group and a terminal hydroxyl group. The Boc protecting group can be removed under acidic conditions. The hydroxyl group can react to further derivatize the compound. The hydrophilic PEG linker increases the water solubility of the compound.
Uses N-Boc-PEG6-alcohol is a PROTAC bridge that belongs to the PEG class and the Alkyl/ether class. N-Boc-PEG6-alcohol can be used to synthesize a series of PROTAC molecules from lookchem. N-Boc-PEG6-alcohol is a cleavable ADC bridge for the synthesis of antibody drug conjugates (ADCs).

Technology Process of N-Boc-PEG6-alcohol

There total 1 articles about N-Boc-PEG6-alcohol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6338-55-2
2-(2-(2-aminoethoxy)ethoxy)ethan-1-ol

: 331242-61-6
tert-butyl N-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamate

Guidance literature:: Multi-step reaction with 3 steps

1: ethanol

2: dmap; triethylamine / dichloromethane / 4 h

3: sodium hydroxide / water; toluene / 100 °C

With dmap; triethylamine; sodium hydroxide; In ethanol; dichloromethane; water; toluene;
DOI:10.1016/j.bmcl.2011.10.078