(2R,3R)-(+)-2,3-BUTANEDIAMINE DIHYDROCHLORIDE

Base Information

• Chemical Name: (2R,3R)-(+)-2,3-BUTANEDIAMINE DIHYDROCHLORIDE
• CAS No.: 66427-25-6
• Molecular Formula: C₄H₁₄N₂*2Cl
• Molecular Weight: 161.075
• Hs Code.: 2921290000
• Mol file: 66427-25-6.mol

Synonyms:(2R,3R)-(+)-2,3-BUTANEDIAMINE DIHYDROCHLORIDE;(R,R)-2,3-DIAMINOBUTANE DIHYDROCHLORIDE

Chemical Property of (2R,3R)-(+)-2,3-BUTANEDIAMINE DIHYDROCHLORIDE

Chemical Property:

• PSA: 52.04000
• LogP: 2.68540

Purity/Quality:

99%min ^*data from raw suppliers

(2R,3R)-(+)-2,3-BUTANEDIAMINE DIHYDROCHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (2R,3R)-(+)-2,3-BUTANEDIAMINE DIHYDROCHLORIDE

There total 4 articles about (2R,3R)-(+)-2,3-BUTANEDIAMINE DIHYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

butane-2,3-dione dioxime (95-45-4) → 2,3-butanediamine dihydrochloride (28971-67-7,41013-42-7,41013-47-2,41013-48-3,55536-62-4,66427-25-6,79595-77-0)

Guidance literature:

With hydrogenchloride; at 5 ℃; cathodic reduction (4F/mol);

Reference yield:

tert-butyl ((2S,3S)-3-aminobutan-2-yl)carbamate → (2S,3S)-2,3-diaminobutane dihydrochloride (28971-67-7,41013-42-7,41013-47-2,41013-48-3,55536-62-4,66427-25-6,79595-77-0)

Guidance literature:

With hydrogenchloride; In methanol; at 5 ℃; for 0.5h; Yield given;

DOI:10.1016/S0957-4166(97)00250-4

Reference yield:

2-azido-3-(3,5-dinitrobenzoylamino)butane → (2S,3S)-2,3-diaminobutane dihydrochloride (28971-67-7,41013-42-7,41013-47-2,41013-48-3,55536-62-4,66427-25-6,79595-77-0) + (2R,3R)-2,3-diaminobutane dihydrochloride

Guidance literature:

Multistep reaction. Title compound not separated from byproducts;

DOI:10.1021/ja061696k

upstream raw materials:

butane-2,3-dione dioxime

Downstream raw materials:

cis-(rac-2,3-diaminobutane)dichloroplatinum(II)

Refernces

• 1、 Fukuta, Yuhei,Mita, Tsuyoshi,Fukuda, Nobuhisa,Kanai, Motomu,Shibasaki, Masakatsu. "De novo synthesis of tamiflu via a catalytic asymmetric ring-opening of meso-aziridines with TMSN3". . p. 6312 - 6313. Retrieved 2007/10/03.
• 2、 Prasad,Yadava,Mishra,Misra. "Electrochemical reduction of ketoximes of some cycloalkanones and 1,2-diones". . p. 95 - 97. Retrieved 2007/10/02.