Benzonitrile, 2-[(tetrahydro-3-Methyl-2,4,6-trioxo-1(2H)-pyriMidinyl)Methyl]-

Base Information

Chemical Name:Benzonitrile, 2-[(tetrahydro-3-Methyl-2,4,6-trioxo-1(2H)-pyriMidinyl)Methyl]-
CAS No.:1246610-72-9
Molecular Formula:C13H11N3O3
Molecular Weight:257.249
Hs Code.:
Mol file:1246610-72-9.mol

Synonyms:Benzonitrile, 2-[(tetrahydro-3-Methyl-2,4,6-trioxo-1(2H)-pyriMidinyl)Methyl]-;Alogliptin-1-oxo-1-de(piperidin-3-amine)

Suppliers and Price of Benzonitrile, 2-[(tetrahydro-3-Methyl-2,4,6-trioxo-1(2H)-pyriMidinyl)Methyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Alogliptin-1-oxo-1-de(piperidin-3-amine)
10mg
$ 165.00

Total 7 raw suppliers

Chemical Property of Benzonitrile, 2-[(tetrahydro-3-Methyl-2,4,6-trioxo-1(2H)-pyriMidinyl)Methyl]-

Chemical Property:

Boiling Point:423.3±47.0 °C(Predicted)
PKA:6.01±0.40(Predicted)
PSA：81.48000
Density:1.39±0.1 g/cm3(Predicted)
LogP:0.74478

Purity/Quality:

95% ^*data from raw suppliers

Alogliptin-1-oxo-1-de(piperidin-3-amine) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Alogliptin-1-oxo-1-de(piperidin-3-amine) is an impurity of Alogliptin (A575425), an oral antihyperglycemic agent that is a selective inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4); Antidiabetic agent.

Technology Process of Benzonitrile, 2-[(tetrahydro-3-Methyl-2,4,6-trioxo-1(2H)-pyriMidinyl)Methyl]-

There total 3 articles about Benzonitrile, 2-[(tetrahydro-3-Methyl-2,4,6-trioxo-1(2H)-pyriMidinyl)Methyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.7%

: 141-82-2
malonic acid

: 1-(2-isocyanatobenzyl)-3-methylurea

: 1246610-72-9
1-(2-cyanobenzyl)-3-methylpyrimidine-2,4,6(1H,3H,5H)-trione

Guidance literature:: With 2-phenyl-6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-2-ium tetrafluoroborate; In methanol; diethyl ether; at 45 ℃; for 1.5h; Concentration; Temperature;