exo-3-AMinoMethyl-8-Boc-8...

Base Information

Chemical Name:exo-3-AMinoMethyl-8-Boc-8...
CAS No.:273207-53-7
Molecular Formula:C13H24N2O2
Molecular Weight:240.346
Hs Code.:2933990090
Mol file:273207-53-7.mol

Synonyms:exo-3-AMinoMethyl-8-Boc-8...;exo-3-AMinoMethyl-8-Boc-8-azabicyclo[3.2.1]octane;exo-tert-Butyl 3-(aminomethyl)-8-azabicyclo[3.2.1]octane-8-carboxylate

Suppliers and Price of exo-3-AMinoMethyl-8-Boc-8...

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
exo-3-Aminomethyl-8-Boc-8-azabicyclo[3.2.1]octane
1 g
$ 300.00

Crysdot
exo-tert-Butyl3-(aminomethyl)-8-azabicyclo[3.2.1]octane-8-carboxylate 95+%
5g
$ 1026.00

Crysdot
exo-tert-Butyl3-(aminomethyl)-8-azabicyclo[3.2.1]octane-8-carboxylate 95+%
1g
$ 342.00

Crysdot
exo-tert-Butyl3-(aminomethyl)-8-azabicyclo[3.2.1]octane-8-carboxylate 95+%
10g
$ 1796.00

Chemenu
tert-butyl(1R,3s,5S)-3-(aminomethyl)-8-azabicyclo[3.2.1]octane-8-carboxylate 97%
25g
$ 1155.00

Chemenu
tert-butyl(1R,3s,5S)-3-(aminomethyl)-8-azabicyclo[3.2.1]octane-8-carboxylate 97%
5g
$ 330.00

Chemenu
tert-butyl(1R,3s,5S)-3-(aminomethyl)-8-azabicyclo[3.2.1]octane-8-carboxylate 97%
10g
$ 583.00

American Custom Chemicals Corporation
EXO-3-AMINOMETHYL-8-BOC-8-AZABICYCLO[3.2.1]OCTANE 95.00%
5MG
$ 453.68

Total 13 raw suppliers

Chemical Property of exo-3-AMinoMethyl-8-Boc-8...

Chemical Property:

Boiling Point:333.9±15.0 °C(Predicted)
PKA:10.11±0.29(Predicted)
PSA：55.56000
Density:1.063±0.06 g/cm3(Predicted)
LogP:2.76140
Storage Temp.:2-8°C(protect from light)

Purity/Quality:

99%, ^*data from raw suppliers

exo-3-Aminomethyl-8-Boc-8-azabicyclo[3.2.1]octane ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of exo-3-AMinoMethyl-8-Boc-8...

There total 5 articles about exo-3-AMinoMethyl-8-Boc-8... which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: tert-butyl (endo)-3-[(benzyloxycarbonyl)amino]methyl-8-azabicyclo[3.2.1]octane-8-carboxylate

: 273207-53-7
tert-butyl (endo)-3-aminomethyl-8-azabicyclo[3.2.1]octane-8-carboxylate

Guidance literature:: With 5%-palladium/activated carbon; hydrogen; In ethanol; ethyl acetate; at 20 ℃; for 14h;

Reference yield:

: methyl [(endo)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl]acetate

: 273207-53-7
tert-butyl (endo)-3-aminomethyl-8-azabicyclo[3.2.1]octane-8-carboxylate

Guidance literature:: Multi-step reaction with 5 steps

1.1: tetrahydrofuran / 1.5 h / Reflux

1.2: 1.5 h / Reflux

2.1: triethylamine / dichloromethane / 5.5 h / 20 °C

3.1: sodium hydroxide; hydrogenchloride / methanol; water / 2 h / 70 °C

4.1: triethylamine; diphenyl phosphoryl azide / 4 h / Reflux

5.1: hydrogen; 5%-palladium/activated carbon / ethanol; ethyl acetate / 14 h / 20 °C

With hydrogenchloride; diphenyl phosphoryl azide; 5%-palladium/activated carbon; hydrogen; triethylamine; sodium hydroxide; In tetrahydrofuran; methanol; ethanol; dichloromethane; water; ethyl acetate;

Reference yield:

: methyl [(endo)-8-azabicyclo[3.2.1]octan-3-yl]acetate hydrochloride

: 273207-53-7
tert-butyl (endo)-3-aminomethyl-8-azabicyclo[3.2.1]octane-8-carboxylate

Guidance literature:: Multi-step reaction with 4 steps

1: triethylamine / dichloromethane / 5.5 h / 20 °C

2: sodium hydroxide; hydrogenchloride / methanol; water / 2 h / 70 °C

3: triethylamine; diphenyl phosphoryl azide / 4 h / Reflux

4: hydrogen; 5%-palladium/activated carbon / ethanol; ethyl acetate / 14 h / 20 °C

With hydrogenchloride; diphenyl phosphoryl azide; 5%-palladium/activated carbon; hydrogen; triethylamine; sodium hydroxide; In methanol; ethanol; dichloromethane; water; ethyl acetate;