ethyl 8-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylate

Base Information

Chemical Name:ethyl 8-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylate
CAS No.:31602-18-3
Molecular Formula:C13H12F3NO2
Molecular Weight:271.24
Hs Code.:2933499090
Mol file:31602-18-3.mol

Synonyms:ethyl 8-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylate

Suppliers and Price of ethyl 8-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
ethyl8-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylate 95
5g
$ 12000.00

Chemenu
Ethyl8-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylate 95%
1g
$ 626.00

Alichem
Ethyl8-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylate
1g
$ 683.40

Alichem
Ethyl8-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylate
250mg
$ 270.68

Total 9 raw suppliers

Chemical Property of ethyl 8-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylate

Chemical Property:

PSA：38.33000
LogP:3.25840

Purity/Quality:

97% ^*data from raw suppliers

ethyl8-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylate 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of ethyl 8-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylate

There total 6 articles about ethyl 8-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 31602-11-6
ethyl 4-chloro-8-(trifluoromethyl)quinoline-3-carboxylate

: 31602-18-3
ethyl 8-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylate

Guidance literature:: With palladium on activated charcoal; hydrogen; In ethanol; at 20 ℃;

Reference yield:

: ethyl 4-oxo-8-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylate

: 31602-18-3
ethyl 8-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: trichlorophosphate / acetonitrile / 7 h / Reflux

2: palladium on activated charcoal; hydrogen / ethanol / 20 °C

With palladium on activated charcoal; hydrogen; trichlorophosphate; In ethanol; acetonitrile;

Reference yield:

: 23779-94-4
2-[(2-trifluoromethylphenylamino)methylene]malonic acid diethyl ester

: 31602-18-3
ethyl 8-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: diphenylether / 12 h / 250 °C

2: trichlorophosphate / acetonitrile / 7 h / Reflux

3: palladium on activated charcoal; hydrogen / ethanol / 20 °C

With diphenylether; palladium on activated charcoal; hydrogen; trichlorophosphate; In ethanol; acetonitrile;