Ethyl 4-chloro-8-(trifluoromethyl)quinoline-3-carboxylate

Base Information

Chemical Name:Ethyl 4-chloro-8-(trifluoromethyl)quinoline-3-carboxylate
CAS No.:31602-11-6
Molecular Formula:C13H9ClF3NO2
Molecular Weight:303.66400
Hs Code.:2933499090
DSSTox Substance ID:DTXSID90352388
Wikidata:Q82129509
Mol file:31602-11-6.mol

Synonyms:31602-11-6;ethyl 4-chloro-8-(trifluoromethyl)quinoline-3-carboxylate;4-Chloro-8-(trifluoromethyl)quinoline-3-carboxylic ethyl ester;4-chloro-8-(trifluoromethyl)quinoline-3-carboxylic acid ethyl ester;MFCD00173388;4-chloro-8-(trifluoromethyl)-3-quinolinecarboxylic acid ethyl ester;SCHEMBL1124642;Ethyl4-chloro-8-(trifluoromethyl)quinoline-3-carboxylate;DTXSID90352388;HMS1694F21;4-Chloro-8-trifluoromethyl-quinoline-3-carboxylic acid ethyl ester;AKOS000535020;SB72417;SY035691;CS-0061589;FT-0735626;6J-027;W18392;A820922;ethyl 4-chloranyl-8-(trifluoromethyl)quinoline-3-carboxylate

Suppliers and Price of Ethyl 4-chloro-8-(trifluoromethyl)quinoline-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
4-Chloro-8-(trifluoromethyl)quinoline-3-carboxylic acid ethyl ester
5 g
$ 928.00

SynQuest Laboratories
4-Chloro-8-(trifluoromethyl)quinoline-3-carboxylic acid ethyl ester
1 g
$ 336.00

Crysdot
Ethyl4-chloro-8-(trifluoromethyl)quinoline-3-carboxylate 95+%
5g
$ 465.00

Chemenu
Ethyl4-chloro-8-(trifluoromethyl)quinoline-3-carboxylate 95%
5g
$ 439.00

Apolloscientific
4-Chloro-8-(trifluoromethyl)quinoline-3-carboxylicacidethylester
5g
$ 580.00

Apolloscientific
4-Chloro-8-(trifluoromethyl)quinoline-3-carboxylicacidethylester
1g
$ 210.00

American Custom Chemicals Corporation
ETHYL 4-CHLORO-8-(TRIFLUOROMETHYL)-3-QUINOLINECARBOXYLATE 95.00%
10G
$ 1891.89

American Custom Chemicals Corporation
ETHYL 4-CHLORO-8-(TRIFLUOROMETHYL)-3-QUINOLINECARBOXYLATE 95.00%
5G
$ 1291.58

American Custom Chemicals Corporation
ETHYL 4-CHLORO-8-(TRIFLUOROMETHYL)-3-QUINOLINECARBOXYLATE 95.00%
1G
$ 806.48

AHH
4-Chloro-8-(trifluoromethyl)quinoline-3-carboxylicethylester 98%
1g
$ 350.00

Total 12 raw suppliers

Chemical Property of Ethyl 4-chloro-8-(trifluoromethyl)quinoline-3-carboxylate

Chemical Property:

Vapor Pressure:9.66E-05mmHg at 25°C
Boiling Point:338.7oC at 760 mmHg
Flash Point:158.6oC
PSA：39.19000
Density:1.401g/cm3
LogP:4.08370
XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:303.0273907
Heavy Atom Count:20
Complexity:364

Purity/Quality:

97% ^*data from raw suppliers

4-Chloro-8-(trifluoromethyl)quinoline-3-carboxylic acid ethyl ester ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 36
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CN=C2C(=C1Cl)C=CC=C2C(F)(F)F

Technology Process of Ethyl 4-chloro-8-(trifluoromethyl)quinoline-3-carboxylate

There total 8 articles about Ethyl 4-chloro-8-(trifluoromethyl)quinoline-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: ethyl 4-oxo-8-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylate

: 31602-11-6
ethyl 4-chloro-8-(trifluoromethyl)quinoline-3-carboxylate

Guidance literature:: With trichlorophosphate; In acetonitrile; for 7h; Reflux;

Reference yield: 76.0%

: 31601-87-3
3-carbethoxy-8-trifluoromethyl-4-quinolone

: 31602-11-6
ethyl 4-chloro-8-(trifluoromethyl)quinoline-3-carboxylate

Guidance literature:: 3-carbethoxy-8-trifluoromethyl-4-quinolone; With trichlorophosphate; for 12h; Heating / reflux;

With sodium hydroxide; In water;