N-(4-ethylphenyl)acetamide

Base Information

• Chemical Name: N-(4-ethylphenyl)acetamide
• CAS No.: 3663-34-1
• Molecular Formula: C10H13NO
• Molecular Weight: 163.219
• Hs Code.: 2924299090
• Mol file: 3663-34-1.mol

Synonyms:4-Ethylacetanilide;p-ethylacetanilide;Acetamide, N-(4-ethylphenyl)-;

Chemical Property of N-(4-ethylphenyl)acetamide

Chemical Property:

• Vapor Pressure: 0.00025mmHg at 25°C
• Boiling Point: 324.2°Cat760mmHg
• Flash Point: 189.8°C
• PSA: 29.10000
• Density: 1.05g/cm³
• LogP: 2.28040

Purity/Quality:

99% ^*data from raw suppliers

4'-ETHYLACETANILIDE AldrichCPR ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of N-(4-ethylphenyl)acetamide

There total 38 articles about N-(4-ethylphenyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

acetic anhydride (108-24-7) + 4-aminoethylbenzene (589-16-2) → N-(4-ethylphenyl)acetamide (3663-34-1)

Guidance literature:

With cadmium(II) oxide; at 80 ℃; for 0.166667h; Neat (no solvent); Microwave irradiation;

Reference yield: 95.0%

1-(p-ethylphenyl)ethanone oxime (2089-32-9) → N-(4-ethylphenyl)acetamide (3663-34-1)

Guidance literature:

With 10-methyl-9-phenylacridin-10-ium perchlorate; In 1,2-dichloro-ethane; at 20 ℃; for 5h; Irradiation; Sealed tube;

DOI:10.1021/acs.orglett.0c02168

Reference yield: 94.0%

N-(4-ethynylphenyl)acetamide (35447-83-7) → N-(4-ethylphenyl)acetamide (3663-34-1)

Guidance literature:

N-(4-ethynylphenyl)acetamide; With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; tricyclohexylphosphine; In 1,4-dioxane; at 20 ℃; for 0.25h; Inert atmosphere;

With formic acid; In 1,4-dioxane; at 80 ℃; chemoselective reaction; Inert atmosphere;

DOI:10.1021/ja2069246

upstream raw materials:

N-ethylacetanilide

4-aminoethylbenzene

ethylbenzene

acetic anhydride

Downstream raw materials:

1-bromo-3-ethylbenzene

N-(2-bromo-4-ethylphenyl)acetamide

acetic acid-(4-ethyl-2-nitro-anilide)

4-ethylthioacetanilide