Ethyl [(5-amino-2-pyridinyl)oxy]acetate

Base Information

Chemical Name:Ethyl [(5-amino-2-pyridinyl)oxy]acetate
CAS No.:203664-68-0
Molecular Formula:C9H12N2O3
Molecular Weight:196.20318
Hs Code.:
DSSTox Substance ID:DTXSID701269428
Mol file:203664-68-0.mol

Synonyms:203664-68-0;Ethyl [(5-amino-2-pyridinyl)oxy]acetate;SCHEMBL6258808;DTXSID701269428;DB-086368;Ethyl 2-[(5-amino-2-pyridinyl)oxy]acetate;Acetic acid,[(5-amino-2-pyridinyl)oxy]-,ethyl ester(9ci)

Suppliers and Price of Ethyl [(5-amino-2-pyridinyl)oxy]acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Ethyl [(5-amino-2-pyridinyl)oxy]acetate

Chemical Property:

PSA：74.44000
LogP:1.18690
XLogP3:0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:196.08479225
Heavy Atom Count:14
Complexity:187

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)COC1=NC=C(C=C1)N

Technology Process of Ethyl [(5-amino-2-pyridinyl)oxy]acetate

There total 2 articles about Ethyl [(5-amino-2-pyridinyl)oxy]acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 392670-15-4
ethyl 2-(5-nitropyridin-2-yloxy)acetate

: 203664-68-0
ethyl 2-(5-aminopyridin-2-yloxy)acetate

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol; Inert atmosphere;
DOI:10.1021/acs.jmedchem.5b01312

Reference yield:

: 4548-45-2
2-chloro-5-nitropyridine

: 203664-68-0
ethyl 2-(5-aminopyridin-2-yloxy)acetate

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydride / tetrahydrofuran; mineral oil / 2 h / 20 °C / Inert atmosphere

2: hydrogen; palladium 10% on activated carbon / methanol / Inert atmosphere

With palladium 10% on activated carbon; hydrogen; sodium hydride; In tetrahydrofuran; methanol; mineral oil;
DOI:10.1021/acs.jmedchem.5b01312