Technology Process of 3-Cyclopentene-1-carboxylicacid,1-(1-methylethyl)-,methylester(9CI)
There total 1 articles about 3-Cyclopentene-1-carboxylicacid,1-(1-methylethyl)-,methylester(9CI) which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
n-butyllithium; diisopropylamine;
In
tetrahydrofuran;
at -78 ℃;
for 0.166667h;
2-iodo-propane; methyl cyclopent-3-ene-1-carboxylate;
In
tetrahydrofuran;
at -78 - 4 ℃;
for 72.75h;
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: dimethylsulfide borane complex / tetrahydrofuran / 20 h / 0 - 20 °C
1.2: 1 h / 0 - 40 °C
2.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 0.17 h / -78 °C
2.2: 0.25 h / -78 °C
2.3: 2 h / 20 °C
3.1: sodium tris(acetoxy)borohydride; N-ethyl-N,N-diisopropylamine / 1,2-dichloro-ethane / 48 h / 20 °C
4.1: potassium hydroxide / ethanol; water / 18 h / Heating / reflux
5.1: 1-hydroxy-7-aza-benzotriazole; 1-ethyl-3-(3-dimethylamino-propyl)-carbodiimide hydrochloride / dichloromethane / 72 h / 20 °C
6.1: methanol; sodium carbonate / bis-triphenylphosphine-palladium(II) chloride / water / 12 h / 80 °C / in a high pressure tube
With
methanol; potassium hydroxide; 1-hydroxy-7-aza-benzotriazole; oxalyl dichloride; dimethylsulfide borane complex; sodium tris(acetoxy)borohydride; sodium carbonate; dimethyl sulfoxide; N-ethyl-N,N-diisopropylamine; 1-ethyl-3-(3-dimethylamino-propyl)-carbodiimide hydrochloride;
bis-triphenylphosphine-palladium(II) chloride;
In
tetrahydrofuran; ethanol; dichloromethane; water; 1,2-dichloro-ethane;
