ethyl 2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate

Base Information

Chemical Name:ethyl 2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate
CAS No.:1245617-64-4
Molecular Formula:C₁₆H₂₃BO₄
Molecular Weight:290.167
Hs Code.:
Mol file:1245617-64-4.mol

Synonyms:ethyl 2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate

Suppliers and Price of ethyl 2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of ethyl 2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate

Chemical Property:

Purity/Quality:: 98%min ^*data from raw suppliers

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Technology Process of ethyl 2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate

There total 3 articles about ethyl 2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 220389-34-4
ethyl 4-bromo-2-methylbenzoate

: 73183-34-3
bis(pinacol)diborane

: 1245617-64-4
ethyl 2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate

Guidance literature:: With potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In dimethyl sulfoxide; at 20 - 80 ℃; for 19h;

Reference yield: 77.0%

: 87-24-1
ethyl 2-methylbenzoate

: 73183-34-3
bis(pinacol)diborane

: 1245617-64-4
ethyl 2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate

Guidance literature:: With (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; 8-([2,2'-bipyridin]-5-yl)quinolin-2(1H)-one; potassium tert-butylate; In tetrahydrofuran; at 80 ℃; for 12h; regioselective reaction; Glovebox; Sealed tube;
DOI:10.1021/jacs.7b04490

Reference yield:

: 118-90-1
ortho-methylbenzoic acid

: 1245617-64-4
ethyl 2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate

Guidance literature:: Multi-step reaction with 2 steps

1: sulfuric acid / 12 h / 100 °C / Sealed tube

2: 8-([2,2'-bipyridin]-5-yl)quinolin-2(1H)-one; potassium tert-butylate; (1,5-cyclooctadiene)(methoxy)iridium(I) dimer / tetrahydrofuran / 12 h / 80 °C / Glovebox; Sealed tube

With (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; sulfuric acid; 8-([2,2'-bipyridin]-5-yl)quinolin-2(1H)-one; potassium tert-butylate; In tetrahydrofuran;
DOI:10.1021/jacs.7b04490