tert-butyl (2S)-2-[(4-phenylthiadiazol-5-yl)carbamoyl]pyrrolidine-1-carboxylate

Base Information

Chemical Name:tert-butyl (2S)-2-[(4-phenylthiadiazol-5-yl)carbamoyl]pyrrolidine-1-carboxylate
CAS No.:1071976-38-9
Molecular Formula:C₁₈H₂₂N₄O₃S
Molecular Weight:374.464
Hs Code.:
Mol file:1071976-38-9.mol

Synonyms:1071976-38-9;SCHEMBL12765472;1-Pyrrolidinecarboxylic acid, 2-[[(4-phenyl-1,2,3-thiadiazol-5-yl)amino]carbonyl]-, 1,1-dimethylethyl ester, (2S)-

Suppliers and Price of tert-butyl (2S)-2-[(4-phenylthiadiazol-5-yl)carbamoyl]pyrrolidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of tert-butyl (2S)-2-[(4-phenylthiadiazol-5-yl)carbamoyl]pyrrolidine-1-carboxylate

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:374.14126175
Heavy Atom Count:26
Complexity:519

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCCC1C(=O)NC2=C(N=NS2)C3=CC=CC=C3
Isomeric SMILES:CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)NC2=C(N=NS2)C3=CC=CC=C3

Technology Process of tert-butyl (2S)-2-[(4-phenylthiadiazol-5-yl)carbamoyl]pyrrolidine-1-carboxylate

There total 2 articles about tert-butyl (2S)-2-[(4-phenylthiadiazol-5-yl)carbamoyl]pyrrolidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 15761-39-4,59433-50-0
1-(tert-butoxycarbonyl)-L-proline

: 78301-72-1
5-amino-4-phenyl-1,2,3-thiadiazole

: 1071976-38-9
(S)-tert-butyl 2-(4-phenyl-1,2,3-thiadiazol-5-ylcarbamoyl)pyrrolidine-1-carboxylate

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 75 ℃;

Reference yield: 77.0%

: 91550-08-2
(S)-2-acetylpyrrolidine-1-carboxylic acid tert-butyl ester

: 78301-72-1
5-amino-4-phenyl-1,2,3-thiadiazole

: 1071976-38-9
(S)-tert-butyl 2-(4-phenyl-1,2,3-thiadiazol-5-ylcarbamoyl)pyrrolidine-1-carboxylate

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 75 ℃;