5-AMINO-1-[4-(-TRIFLUOROMETHYL)PHENYL]-1H-PYRAZOLE-3-CARBONITRILE

Base Information

Chemical Name:5-AMINO-1-[4-(-TRIFLUOROMETHYL)PHENYL]-1H-PYRAZOLE-3-CARBONITRILE
CAS No.:1020057-82-2
Molecular Formula:C₁₁H₇F₃N₄
Molecular Weight:252.199
Hs Code.:
Mol file:1020057-82-2.mol

Synonyms:5-AMINO-1-[4-(-TRIFLUOROMETHYL)PHENYL]-1H-PYRAZOLE-3-CARBONITRILE

Suppliers and Price of 5-AMINO-1-[4-(-TRIFLUOROMETHYL)PHENYL]-1H-PYRAZOLE-3-CARBONITRILE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
5-AMINO-1-[4-(-TRIFLUOROMETHYL)PHENYL]-1H- PYRAZOLE-3-CARBONITRILE 95.00%
5MG
$ 505.04

Total 2 raw suppliers

Chemical Property of 5-AMINO-1-[4-(-TRIFLUOROMETHYL)PHENYL]-1H-PYRAZOLE-3-CARBONITRILE

Chemical Property:

Boiling Point:400.4±45.0 °C(Predicted)
PKA:-0.46±0.14(Predicted)
PSA：67.63000
Density:1.43±0.1 g/cm3(Predicted)
LogP:2.92618

Purity/Quality:

98% ^*data from raw suppliers

5-AMINO-1-[4-(-TRIFLUOROMETHYL)PHENYL]-1H- PYRAZOLE-3-CARBONITRILE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-AMINO-1-[4-(-TRIFLUOROMETHYL)PHENYL]-1H-PYRAZOLE-3-CARBONITRILE

There total 1 articles about 5-AMINO-1-[4-(-TRIFLUOROMETHYL)PHENYL]-1H-PYRAZOLE-3-CARBONITRILE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 455-14-1
4-trifluoromethylphenylamine

: 1020057-82-2
5-amino-1-(4-trifluoromethylphenyl)-3-cyano-1H-pyrazole

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride; sodium nitrite / ethanol; water / 0.5 h / Cooling with ice

2: 2 h

With hydrogenchloride; sodium nitrite; In ethanol; water;

Reference yield:

: 1020057-82-2
5-amino-1-(4-trifluoromethylphenyl)-3-cyano-1H-pyrazole

: diethyl ((5-(4-chlorophenyl)furan-2-yl)((3-cyano-1-(4-trifluoromethylphenyl)-1H-pyrazole-5-yl)amino)methyl)phosphonate

Guidance literature:: Multi-step reaction with 2 steps

1: piperidine / toluene / Reflux

2: Heating

With piperidine; In toluene;
DOI:10.1080/10426507.2017.1334653

Reference yield:

: 1020057-82-2
5-amino-1-(4-trifluoromethylphenyl)-3-cyano-1H-pyrazole

: diethyl(((3-cyano-1-(4-trifluoromethylphenyl)-1H-pyrazol-5-yl)amino)(4-fluorophenyl)methyl)phosphonate

Guidance literature:: Multi-step reaction with 2 steps

1: toluene / Reflux

2: 8 h / 70 °C

In toluene; 2: |Pudovik Reaction;
DOI:10.1080/10426507.2016.1166365