Methyl 3-(dibroMoMethyl)picolinate

Base Information

• Chemical Name: Methyl 3-(dibroMoMethyl)picolinate
• CAS No.: 1029720-23-7
• Molecular Formula: C8H7Br2NO2
• Molecular Weight: 308.95468
• Hs Code.: 2933399090
• Mol file: 1029720-23-7.mol

Synonyms:Methyl 3-(dibroMoMethyl)picolinate

Chemical Property of Methyl 3-(dibroMoMethyl)picolinate

Chemical Property:

• PSA: 39.19000
• LogP: 2.65660
• Storage Temp.: 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

Methyl3-(dibromomethyl)picolinate >95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Methyl 3-(dibroMoMethyl)picolinate

There total 3 articles about Methyl 3-(dibroMoMethyl)picolinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

3-methyl-pyridine-2-carboxylic acid methyl ester (59718-84-2) → methyl 3-(dibromomethyl)pyridine-2-carboxylate (1029720-23-7)

Guidance literature:

With N-Bromosuccinimide; In tetrachloromethane; for 16h; Reflux;

DOI:10.1016/j.tet.2013.06.029

Reference yield:

3-methyl-pyridine-2-carboxylic acid (4021-07-2) → methyl 3-(dibromomethyl)pyridine-2-carboxylate (1029720-23-7)

Guidance literature:

Multi-step reaction with 2 steps

1: sulfuric acid / Reflux

2: N-Bromosuccinimide / tetrachloromethane / 16 h / Reflux

With N-Bromosuccinimide; sulfuric acid; In tetrachloromethane;

DOI:10.1016/j.tet.2013.06.029

Reference yield:

2-cyano-3-methylpyridine (20970-75-6) → methyl 3-(dibromomethyl)pyridine-2-carboxylate (1029720-23-7)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium hydroxide; water

2: sulfuric acid / Reflux

3: N-Bromosuccinimide / tetrachloromethane / 16 h / Reflux

With N-Bromosuccinimide; sulfuric acid; water; potassium hydroxide; In tetrachloromethane;

DOI:10.1016/j.tet.2013.06.029

upstream raw materials:

3-methyl-pyridine-2-carboxylic acid

3-methyl-pyridine-2-carboxylic acid methyl ester

2-cyano-3-methylpyridine

Downstream raw materials:

pyrido[2,3-d]pyridazin-8(7H)-one

Refernces